Sudden unexpected death in epilepsy: epidemiology, mechanisms, and prevention

O Devinsky, DC Hesdorffer, DJ Thurman… - The Lancet …, 2016 - thelancet.com
Sudden unexpected death in epilepsy (SUDEP) can affect individuals of any age, but is most
common in younger adults (aged 20–45 years). Generalised tonic-clonic seizures are the …

[HTML][HTML] Sudden unexpected death in epilepsy: The neuro-cardio-respiratory connection

TA Manolis, AA Manolis, H Melita, AS Manolis - Seizure, 2019 - Elsevier
Sudden unexpected death in epilepsy (SUDEP) is the major cause of epilepsy-related
premature mortality which targets preferentially younger people. Its etiology remains …

Seizure semiology: ILAE glossary of terms and their significance

S Beniczky, WO Tatum, H Blumenfeld, H Stefan… - Epileptic …, 2022 - stm.cairn.info
2. Tatum W, Rubboli G, Kaplan P, Mirsatari S, Radhakrishnan K, Gloss D, et al. Clinical utility
of EEG in diagnosing and monitoring epilepsy in adults. Clin Neurophysiol 2018; 129 (5) …

Postconvulsive central apnea as a biomarker for sudden unexpected death in epilepsy (SUDEP)

L Vilella, N Lacuey, JP Hampson, MRS Rani… - Neurology, 2019 - AAN Enterprises
Objective To characterize peri-ictal apnea and postictal asystole in generalized convulsive
seizures (GCS) of intractable epilepsy. Methods This was a prospective, multicenter epilepsy …

Brainstem spreading depolarization and cortical dynamics during fatal seizures in Cacna1a S218L mice

ICM Loonen, NA Jansen, SM Cain, M Schenke… - Brain, 2019 - academic.oup.com
Sudden unexpected death in epilepsy (SUDEP) is a fatal complication of epilepsy in which
brainstem spreading depolarization may play a pivotal role, as suggested by animal studies …

Bidirectional relationships of sleep and epilepsy in adults with epilepsy

M Grigg-Damberger, N Foldvary-Schaefer - Epilepsy & Behavior, 2021 - Elsevier
This targeted review addresses the best accepted and most intriguing recent observations
on the complex relationships between sleep and epilepsy. Ten to 15% of all epilepsies are …

Wearable devices for sudden unexpected death in epilepsy prevention

P Ryvlin, C Ciumas, I Wisniewski, S Beniczky - Epilepsia, 2018 - Wiley Online Library
Sudden unexpected death in epilepsy (SUDEP) is most often associated with the
occurrence of generalized tonic–clonic seizures (GTCS), a seizure type that can now be …

Incidence, recurrence, and risk factors for peri-ictal central apnea and sudden unexpected death in epilepsy

L Vilella, N Lacuey, JP Hampson, MRS Rani… - Frontiers in …, 2019 - frontiersin.org
Introduction: Peri-ictal breathing dysfunction was proposed as a potential mechanism for
SUDEP. We examined the incidence and risk factors for both ictal (ICA) and post-convulsive …

Postictal immobility and generalized EEG suppression are associated with the severity of respiratory dysfunction

J Kuo, W Zhao, CS Li, JD Kennedy, M Seyal - Epilepsia, 2016 - Wiley Online Library
Objective The pathophysiology of sudden unexpected death in epilepsy (SUDEP) remains
undetermined. Seizures are accompanied by respiratory dysfunction (RD). Postictal …

Hypoxemia following generalized convulsive seizures: risk factors and effect of oxygen therapy

S Rheims, BM Alvarez, V Alexandre, J Curot… - Neurology, 2019 - AAN Enterprises
Objective To analyze the factors that determine the occurrence or severity of postictal
hypoxemia in the immediate aftermath of a generalized convulsive seizure (GCS). Methods …