Interaction of SARS-CoV-2 with host cells and antibodies: experiment and simulation
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is the causative agent of
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
the devastating global COVID-19 pandemic announced by WHO in March 2020. Through …
Cardiomyopathy associated with anti-SARS-CoV-2 vaccination: what do we know?
A Parra-Lucares, L Toro, S Weitz-Muñoz, C Ramos - Viruses, 2021 - mdpi.com
The SARS-CoV-2 pandemic has mobilized many efforts worldwide to curb its impact on
morbidity and mortality. Vaccination of the general population has resulted in the …
morbidity and mortality. Vaccination of the general population has resulted in the …
Quantitative profiling of N-glycosylation of SARS-CoV-2 spike protein variants
With the global spread of the corona virus disease-2019 pandemic, new spike variants of
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continuously emerge due …
severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) continuously emerge due …
[HTML][HTML] SARS-CoV-2 spike binding to ACE2 is stronger and longer ranged due to glycan interaction
Highly detailed steered molecular dynamics simulations are performed on differently
glycosylated receptor binding domains of the severe acute respiratory syndrome …
glycosylated receptor binding domains of the severe acute respiratory syndrome …
Modeling identifies variability in SARS-CoV-2 uptake and eclipse phase by infected cells as principal drivers of extreme variability in nasal viral load in the 48 h post …
The SARS-CoV-2 coronavirus continues to evolve with scores of mutations of the spike,
membrane, envelope, and nucleocapsid structural proteins that impact pathogenesis …
membrane, envelope, and nucleocapsid structural proteins that impact pathogenesis …
Antibody protection from SARS-CoV-2 respiratory tract exposure and infection
The COVID-19 pandemic has underscored the need to understand the dynamics of SARS-
CoV-2 respiratory infection and protection provided by the immune response. SARS-CoV-2 …
CoV-2 respiratory infection and protection provided by the immune response. SARS-CoV-2 …
Point mutations in SARS-CoV-2 variants induce long-range dynamical perturbations in neutralizing antibodies
Monoclonal antibodies are emerging as a viable treatment for the coronavirus disease 19
(COVID-19). However, newly evolved variants of the severe acute respiratory syndrome …
(COVID-19). However, newly evolved variants of the severe acute respiratory syndrome …
Impact of the temperature on the interactions between common variants of the SARS-CoV-2 receptor binding domain and the human ACE2
C Forest-Nault, I Koyuturk, J Gaudreault, A Pelletier… - Scientific Reports, 2022 - nature.com
Several key mutations in the Spike protein receptor binding domain (RBD) have been
identified to influence its affinity for the human Angiotensin-Converting Enzyme 2 (ACE2) …
identified to influence its affinity for the human Angiotensin-Converting Enzyme 2 (ACE2) …
Exploring CRD mobility during RAS/RAF engagement at the membrane
During the activation of mitogen-activated protein kinase (MAPK) signaling, the RAS-binding
domain (RBD) and cysteine-rich domain (CRD) of RAF bind to active RAS at the plasma …
domain (RBD) and cysteine-rich domain (CRD) of RAF bind to active RAS at the plasma …
Many roles of carbohydrates: A computational spotlight on the coronavirus S protein binding
Glycosylation is one of the post-translational modifications with more than 50% of human
proteins being glycosylated. The exact nature and chemical composition of glycans are …
proteins being glycosylated. The exact nature and chemical composition of glycans are …