Current concepts in intracranial interstitial fluid transport and the glymphatic system: part II—imaging techniques and clinical applications

JM Klostranec, D Vucevic, KD Bhatia, HGJ Kortman… - Radiology, 2021 - pubs.rsna.org
The glymphatic system is a recently discovered network unique to the central nervous
system that allows for dynamic exchange of interstitial fluid (ISF) and cerebrospinal fluid …

Glymphatic imaging using MRI

T Taoka, S Naganawa - Journal of Magnetic Resonance …, 2020 - Wiley Online Library
In recent years, the existence of a mass transport system in the brain via cerebrospinal fluid
(CSF) or interstitial fluid (ISF) has been suggested by many studies. The glymphatic system …

The glymphatic system: a review of the challenges in visualizing its structure and function with MR imaging

S Naganawa, T Taoka - Magnetic Resonance in Medical Sciences, 2022 - jstage.jst.go.jp
The central nervous system (CNS) was previously thought to be the only organ system
lacking lymphatic vessels to remove waste products from the interstitial space. Recently …

Four‐dimensional flow MRI for quantitative assessment of cerebrospinal fluid dynamics: Status and opportunities

LA Rivera‐Rivera, T Vikner, L Eisenmenger… - NMR in …, 2024 - Wiley Online Library
Neurological disorders can manifest with altered neurofluid dynamics in different
compartments of the central nervous system. These include alterations in cerebral blood …

[HTML][HTML] Assessing pulsatile waveforms of paravascular cerebrospinal fluid dynamics within the glymphatic pathways using dynamic diffusion-weighted imaging (dDWI …

Q Wen, Y Tong, X Zhou, M Dzemidzic, CY Ho, YC Wu - Neuroimage, 2022 - Elsevier
Cerebrospinal fluid (CSF) in the paravascular spaces of the surface arteries (sPVS) is a vital
pathway in brain waste clearance. Arterial pulsations may be the driving force of the …

Neurofluids and the glymphatic system: anatomy, physiology, and imaging

DJJ Wang, J Hua, D Cao, ML Ho - The British journal of …, 2023 - academic.oup.com
First described in 2012, the glymphatic system is responsible for maintaining homeostasis
within the central nervous system, including nutrient delivery, waste clearance, and …

[HTML][HTML] The Cerebrovascular Side of Plasticity: Microvascular Architecture across Health and Neurodegenerative and Vascular Diseases

M Zedde, R Pascarella - Brain Sciences, 2024 - mdpi.com
The delivery of nutrients to the brain is provided by a 600 km network of capillaries and
microvessels. Indeed, the brain is highly energy demanding and, among a total amount of …

Clinical magnetic resonance imaging evaluation of glymphatic function

ED Boyd, J Kaur, G Ding, M Chopp… - NMR in …, 2024 - Wiley Online Library
The glymphatic system is a system of specialized perivascular spaces in the brain that
facilitates removal of toxic waste solutes from the brain. Evaluation of glymphatic system …

Limits to flow detection in phase contrast MRI

NH Williamson, ME Komlosh, D Benjamini… - Journal of magnetic …, 2020 - Elsevier
Pulsed gradient spin echo (PGSE) complex signal behavior becomes dominated by
attenuation rather than oscillation when displacements due to flow are similar or less than …

Investigation of contrast mechanisms for MRI phase signal‐based proton beam visualization in water phantoms

J Schieferecke, S Gantz, A Hoffmann… - Magnetic Resonance …, 2023 - Wiley Online Library
Purpose The low sensitivity and limitation to water phantoms of convection‐dependent MRI
magnitude signal‐based proton beam visualization hinder its in vivo applicability in MR …