A review of sorting, separation and isolation of cells and microbeads for biomedical applications: microfluidic approaches

A Dalili, E Samiei, M Hoorfar - Analyst, 2019 - pubs.rsc.org
Several biomedical analyses are performed on particular types of cells present in body
samples or using functionalized microparticles. Success in such analyses depends on the …

Particle separation and sorting in microfluidic devices: a review

P Sajeesh, AK Sen - Microfluidics and nanofluidics, 2014 - Springer
Separation and sorting of micron-sized particles has great importance in diagnostics,
chemical and biological analyses, food and chemical processing and environmental …

Microfluidic, marker-free isolation of circulating tumor cells from blood samples

NM Karabacak, PS Spuhler, F Fachin, EJ Lim, V Pai… - Nature protocols, 2014 - nature.com
The ability to isolate and analyze rare circulating tumor cells (CTCs) has the potential to
further our understanding of cancer metastasis and enhance the care of cancer patients. In …

Deterministic lateral displacement: Challenges and perspectives

A Hochstetter, R Vernekar, RH Austin, H Becker… - ACS …, 2020 - ACS Publications
The advent of microfluidics in the 1990s promised a revolution in multiple industries from
healthcare to chemical processing. Deterministic lateral displacement (DLD) is a continuous …

Inertial focusing in microfluidics

JM Martel, M Toner - Annual review of biomedical engineering, 2014 - annualreviews.org
When Segré and Silberberg in 1961 witnessed particles in a laminar pipe flow congregating
at an annulus in the pipe, scientists were perplexed and spent decades learning why such …

Design of pressure-driven microfluidic networks using electric circuit analogy

KW Oh, K Lee, B Ahn, EP Furlani - Lab on a Chip, 2012 - pubs.rsc.org
This article reviews the application of electric circuit methods for the analysis of pressure-
driven microfluidic networks with an emphasis on concentration-and flow-dependent …

Passive microfluidic devices for cell separation

T Zhang, D Di Carlo, CT Lim, T Zhou, G Tian… - Biotechnology …, 2024 - Elsevier
The separation of specific cell populations is instrumental in gaining insights into cellular
processes, elucidating disease mechanisms, and advancing applications in tissue …

Advancements in microfluidics for nanoparticle separation

T Salafi, KK Zeming, Y Zhang - Lab on a Chip, 2017 - pubs.rsc.org
Nanoparticles have been widely implemented for healthcare and nanoscience industrial
applications. Thus, efficient and effective nanoparticle separation methods are essential for …

A review on deterministic lateral displacement for particle separation and detection

T Salafi, Y Zhang, Y Zhang - Nano-Micro Letters, 2019 - Springer
The separation and detection of particles in suspension are essential for a wide spectrum of
applications including medical diagnostics. In this field, microfluidic deterministic lateral …

Tumor-derived microvesicles: shedding light on novel microenvironment modulators and prospective cancer biomarkers

C D'Souza-Schorey, JW Clancy - Genes & development, 2012 - genesdev.cshlp.org
Recent advances in the study of tumor-derived microvesicles reveal new insights into the
cellular basis of disease progression and the potential to translate this knowledge into …