Filamentous fungi constitute a large group of eukaryotic microorganisms that grow by
forming simple tube-like hyphae that are capable of differentiating into more-complex …

The organization of microtubule networks is crucial for controlling chromosome segregation
during cell division, for positioning and transport of different organelles, and for cell polarity …

Centrosomes are important cell organizers. They consist of a pair of centrioles surrounded
by pericentriolar material (PCM) that expands dramatically during mitosis—a process termed …

Organisms with closed or open mitosis have differentially evolved various gamma-tubulin
complex (γ-TuC) recruiting factors to organize diverse cellular microtubule (MT) arrays …

Autosomal recessive primary microcephaly (MCPH) is characterized by small brain size as a
result of deficient neuron production in the develo** cerebral cortex. Although MCPH is a …

Cdc15p is known to contribute to cytokinesis in fission yeast; however, the protein is not
required to assemble the contractile ring of actin and myosin, but it helps to anchor the ring …

Budding yeast Spc110, a member of γ-tubulin complex receptor family (γ-TuCR), recruits γ-
tubulin complexes to microtubule (MT) organizing centers (MTOCs). Biochemical studies …

To establish the microtubule cytoskeleton, the cell must tightly regulate when and where
microtubules are nucleated. This regulation involves controlling the initial nucleation …

The centrosome is the major microtubule organizing centre (MTOC) in animal cells. The
canonical centrosome is composed of two centrioles surrounded by a pericentriolar matrix …

An organised spindle is crucial to the fidelity of chromosome segregation, but the
relationship between spindle structure and function is not well understood in any cell type …