RNA-binding proteins (RBPs) can regulate gene expression through post-transcriptionally
influencing all manner of RNA biology, including alternative splicing (AS), polyadenylation …

Despite the recent progress in cancer management approaches, the mortality rate of cancer
is still growing and there are lots of challenges in the clinics in terms of novel therapeutics …

Mature microRNAs (miRNAs) are single-stranded RNA molecules of 20–23-nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

Background The use of biomarkers for prostate cancer screening, diagnosis and prognosis
has the potential to improve the clinical management of the patients. Owing to inherent …

MicroRNA (miRNA; miR) is a functionally small non-coding RNA and can negatively
regulate gene expression by directly binding to the target gene. Some miRNAs are closely …

Mature microRNAs (miRNAs) are single‐stranded RNA molecules of 20–23 nucleotide (nt)
length that control gene expression in many cellular processes. These molecules typically …

When,∼ 20 years ago, investigators first determined that components of the genome
considered nonfunctional had, in fact, gene regulatory capacity, they probably had no idea …

In recent years, the importance of epigenetic markers in the carcinogenesis of different
malignant neoplasms has been demonstrated, also demonstrating their utility for …

Despite the decline in death rate from breast cancer and recent advances in targeted
therapies and combinations for the treatment of metastatic disease, metastatic breast cancer …

Through in vivo selection of human cancer cell populations, we uncover a convergent and
cooperative miRNA network that drives melanoma metastasis. We identify miR-1908, miR …