The stomach is traditionally regarded as a hollow muscular sac that initiates the second
phase of digestion. Yet this simple view ignores the fact that it is the most sophisticated …

Gastric adenocarcinoma (GC) is the third leading cause of global cancer mortality, and the
leading infection-associated cancer with more than 1 million incident cases annually and …

Invasive gastric carcinoma is preceded by a cascade of precancerous lesions. The first
recognized histologic change is active chronic inflammation, which may persist as such: non …

At the end of the last century, a far-sighted 'working party'held in Sydney, Australia
addressed the clinicopathological issues related to gastric inflammatory diseases. A few …

BACKGROUND: The OLGA (operative link on gastritis assessment) staging system is based
on severity of atrophic gastritis (AG). AG remains a difficult histopathologic diagnosis with …

Gastric cancer, 1 of the 5 most common causes of cancer death, is associated with a 5-year
overall survival rate less than 30%. A minority of cancers occurs as part of syndromic …

International consensus meetings in Padova and Vienna have attempted to rationalise the
grading and classification of gastrointestinal epithelial neoplasia (GEN). With its minor …

Helicobacter infection is the leading cause of gastric cancer worldwide. Infection with this
ubiquitous bacterium incites a chronic active immune response that persists for the life of the …

Objective To evaluate the long-term effect of cumulative time exposed to Helicobacter pylori
infection on the progression of gastric lesions. Design 795 adults with precancerous gastric …

Background and Aims Although the incidence of gastric cancer in the United States is
relatively low, the incidence of gastric cancer is higher than for esophageal cancer, for which …