The problem of resistance to therapy in cancer is multifaceted. Here we take a reductionist
approach to define and separate the key determinants of drug resistance, which include …

Targeting nanoparticles to malignant tissues for improved diagnosis and therapy is a
popular concept. However, after surveying the literature from the past 10 years, only …

Nanoparticle‐based therapeutic, prevention, and detection modalities have the potential to
greatly impact how diseases are diagnosed and managed in the clinic. With the wide range …

Significant progress has been made in circular RNA (circRNA) research in recent years.
Increasing evidence suggests that circRNAs play important roles in many cellular processes …

Gene-based therapy is the intentional modulation of gene expression in specific cells to treat
pathological conditions. This modulation is accomplished by introducing exogenous nucleic …

Nanotechnology has recently gained increased attention for its capability to effectively
diagnose and treat various tumors. Nanocarriers have been used to circumvent the …

Two-dimensional (2D) materials are at the forefront of materials research. Here we overview
their applications beyond graphene, such as transition metal dichalcogenides …

In medicine, nanotechnology has sparked a rapidly growing interest as it promises to solve a
number of issues associated with conventional therapeutic agents, including their poor …

Nanomaterial (NM) delivery to solid tumors has been the focus of intense research for over a
decade. Classically, scientists have tried to improve NM delivery by employing passive or …

Nanoparticle/microparticle‐based drug delivery systems for systemic (ie, intravenous)
applications have significant advantages over their nonformulated and free drug …