Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …

Decreased skeletal muscle contractile activity (disuse) or unloading leads to muscle mass
loss, also known as muscle atrophy. The balance between muscle protein synthesis (MPS) …

One of the most striking adaptations to exercise is the skeletal muscle hypertrophy that
occurs in response to resistance exercise. A large body of work shows that a mammalian …

Maintenance of skeletal muscle mass is regulated by the balance between anabolic and
catabolic processes. Mammalian target of rapamycin (mTOR) is an evolutionarily conserved …

Physical exercise has beneficial effects on metabolic diseases, and a combined therapeutic
regimen of regular exercise and pharmaceutical treatment is often recommended for their …

In the last few years, the muscular system has gained attention due to the discovery of the
muscle-secretome and its high potency for retaining or regaining health. These cytokines …

This investigation compared the effect of high‐volume (VOL) versus high‐intensity (INT)
resistance training on stimulating changes in muscle size and strength in resistance‐trained …

Muscle protein synthesis (MPS) is the driving force behind adaptive responses to exercise
and represents a widely adopted proxy for gauging chronic efficacy of acute interventions,(ie …

Mammalian skeletal muscles are composed of a variety of highly specialized fibers whose
selective recruitment allows muscles to fulfill their diverse functional tasks. In addition …

Skeletal muscle is crucial for movement and whole-body metabolism; therefore, the
maintenance of skeletal muscle mass is essential for mobility, disease prevention, and …