Guidelines and considerations for the use of system suitability and quality control samples in mass spectrometry assays applied in untargeted clinical metabolomic …

D Broadhurst, R Goodacre, SN Reinke, J Kuligowski… - Metabolomics, 2018 - Springer
Background Quality assurance (QA) and quality control (QC) are two quality management
processes that are integral to the success of metabolomics including their application for the …

TFOS DEWS II tear film report

MDP Willcox, P Argüeso, GA Georgiev, JM Holopainen… - The ocular …, 2017 - Elsevier
The members of the Tear Film Subcommittee reviewed the role of the tear film in dry eye
disease (DED). The Subcommittee reviewed biophysical and biochemical aspects of tears …

The microbiome of professional athletes differs from that of more sedentary subjects in composition and particularly at the functional metabolic level

W Barton, NC Penney, O Cronin, I Garcia-Perez… - Gut, 2018 - gut.bmj.com
Objective It is evident that the gut microbiota and factors that influence its composition and
activity effect human metabolic, immunological and developmental processes. We …

Diagnosis and prognosis of breast cancer by high-performance serum metabolic fingerprints

Y Huang, S Du, J Liu, W Huang, W Liu, M Zhang… - Proceedings of the …, 2022 - pnas.org
High-performance metabolic analysis is emerging in the diagnosis and prognosis of breast
cancer (BrCa). Still, advanced tools are in demand to deliver the application potentials of …

PD-1 signaling limits expression of phospholipid phosphatase 1 and promotes intratumoral CD8+ T cell ferroptosis

Y **, J Shan, H Qin, F Li, J Qu, R Guo, D Han, W **g… - Immunity, 2024 - cell.com
The tumor microenvironment (TME) promotes metabolic reprogramming and dysfunction in
immune cells. Here, we examined the impact of the TME on phospholipid metabolism in …

Analysis of the human adult urinary metabolome variations with age, body mass index, and gender by implementing a comprehensive workflow for univariate and …

EA Thévenot, A Roux, Y Xu, E Ezan… - Journal of proteome …, 2015 - ACS Publications
Urine metabolomics is widely used for biomarker research in the fields of medicine and
toxicology. As a consequence, characterization of the variations of the urine metabolome …

The Synergistic Effects of Polysaccharides and Ginsenosides From American Ginseng (Panax quinquefolius L.) Ameliorating Cyclophosphamide-Induced Intestinal …

R Zhou, D He, J **e, Q Zhou, H Zeng, H Li… - Frontiers in …, 2021 - frontiersin.org
Cyclophosphamide (CTX), used in cancer chemotherapy, a high dose of which would cause
immunosuppressive effect and intestinal mucosa damage. American ginseng (Panax …

Microplastics dampen the self-renewal of hematopoietic stem cells by disrupting the gut microbiota-hypoxanthine-Wnt axis

L Jiang, Y Ye, Y Han, Q Wang, H Lu, J Li, W Qian… - Cell discovery, 2024 - nature.com
Microplastics (MPs) are contaminants ubiquitously found in the global biosphere that enter
the body through inhalation or ingestion, posing significant risks to human health. Recent …

[HTML][HTML] The human urine metabolome

S Bouatra, F Aziat, R Mandal, AC Guo, MR Wilson… - PloS one, 2013 - journals.plos.org
Urine has long been a “favored” biofluid among metabolomics researchers. It is sterile, easy-
to-obtain in large volumes, largely free from interfering proteins or lipids and chemically …

Advances in mass spectrometry-based metabolomics for investigation of metabolites

JL Ren, AH Zhang, L Kong, XJ Wang - RSC advances, 2018 - pubs.rsc.org
Metabolomics is the systematic study of all the metabolites present within a biological
system, which consists of a mass of molecules, having a variety of physical and chemical …