Traumatic spinal cord injury: an overview of pathophysiology, models and acute injury mechanisms
Traumatic spinal cord injury (SCI) is a life changing neurological condition with substantial
socioeconomic implications for patients and their care-givers. Recent advances in medical …
socioeconomic implications for patients and their care-givers. Recent advances in medical …
Rat models of spinal cord injury: from pathology to potential therapies
J Kjell, L Olson - Disease models & mechanisms, 2016 - journals.biologists.com
ABSTRACT A long-standing goal of spinal cord injury research is to develop effective spinal
cord repair strategies for the clinic. Rat models of spinal cord injury provide an important …
cord repair strategies for the clinic. Rat models of spinal cord injury provide an important …
[HTML][HTML] Exosomal miR-155 from M1-polarized macrophages promotes EndoMT and impairs mitochondrial function via activating NF-κB signaling pathway in vascular …
X Ge, P Tang, Y Rong, D Jiang, X Lu, C Ji, J Wang… - Redox biology, 2021 - Elsevier
Abstract Pathologically, blood-spinal-cord-barrier (BSCB) disruption after spinal cord injury
(SCI) leads to infiltration of numerous peripheral macrophages into injured areas and …
(SCI) leads to infiltration of numerous peripheral macrophages into injured areas and …
Spinal cord injury models: a review
Background: Animal spinal cord injury (SCI) models have proved invaluable in better
understanding the mechanisms involved in traumatic SCI and evaluating the effectiveness of …
understanding the mechanisms involved in traumatic SCI and evaluating the effectiveness of …
Restoration of sensorimotor functions after spinal cord injury
The purpose of this review is to discuss the achievements and perspectives regarding
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …
rehabilitation of sensorimotor functions after spinal cord injury. In the first part we discuss …
Pre-evaluated safe human iPSC-derived neural stem cells promote functional recovery after spinal cord injury in common marmoset without tumorigenicity
Y Kobayashi, Y Okada, G Itakura, H Iwai, S Nishimura… - PloS one, 2012 - journals.plos.org
Murine and human iPSC-NS/PCs (induced pluripotent stem cell-derived neural
stem/progenitor cells) promote functional recovery following transplantation into the injured …
stem/progenitor cells) promote functional recovery following transplantation into the injured …
Proprioception and locomotor disorders
V Dietz - Nature Reviews Neuroscience, 2002 - nature.com
Advances in our understanding of movement control allow us to define more precisely the
requirements for the rehabilitation of patients with movement disorders. Most purposeful …
requirements for the rehabilitation of patients with movement disorders. Most purposeful …
Spinal cord pattern generators for locomotion
V Dietz - Clinical Neurophysiology, 2003 - Elsevier
It is generally accepted that locomotion in mammals, including humans, is based on the
activity of neuronal circuits within the spinal cord (the central pattern generator, CPG) …
activity of neuronal circuits within the spinal cord (the central pattern generator, CPG) …
Cell death in models of spinal cord injury
MS Beattie, GE Hermann, RC Rogers… - Progress in brain …, 2002 - Elsevier
Current treatments for acute spinal cord injury are based on animal models of human spinal
cord injury (SCI). These models have shown that the initial traumatic injury to cord tissue is …
cord injury (SCI). These models have shown that the initial traumatic injury to cord tissue is …
Recovery of locomotion after spinal cord injury: some facts and mechanisms
S Rossignol, A Frigon - Annual review of neuroscience, 2011 - annualreviews.org
After spinal cord injury (SCI), various sensorimotor functions can recover, ranging from
simple spinal reflexes to more elaborate motor patterns, such as locomotion. Locomotor …
simple spinal reflexes to more elaborate motor patterns, such as locomotion. Locomotor …