Microbial communities are shaped by positive and negative interactions ranging from
competition to mutualism. In the context of the mammalian gut and its microbial inhabitants …

Microbial communities drive global biogeochemical cycles and shape the health of plants
and animals—including humans. Their structure and function are determined by ecological …

Engineering natural microbiomes for biotechnological applications remains challenging, as
metabolic interactions within microbiomes are largely unknown, and practical principles and …

Bacterial drug resistance is rapidly develo** as one of the greatest threats to human
health. Bacteria will adopt corresponding strategies to crack the inhibitory effect of antibiotics …

Many microorganisms are auxotrophic—unable to synthesize the compounds they require
for growth. With this work, we quantify the prevalence of amino acid auxotrophies across a …

Communities of microbes play important roles in natural environments and hold great
potential for deploying division-of-labor strategies in synthetic biology and bioproduction …

Exploring microbial stress responses to drugs is crucial for the advancement of new
therapeutic methods. While current artificial intelligence methodologies have expedited our …

Infections that involve interkingdom microbial communities, such as those between bacteria
and yeast pathogens, are difficult to treat, associated with worse patient outcomes, and may …

Fungal infections are increasing globally, causing alarmingly high mortality and economic
burden. In addition to antifungal resistance, other more subtle drug responses appear to …

Background A growing body of evidence suggests that the gut microbiota is strongly linked
to general human health. Microbiome-directed interventions, such as diet and exercise, are …