Increasing the efficacy of approved systemic treatments in metastasized pancreatic
neuroendocrine tumors (PanNET) is an unmet medical need. The antiangiogenic tyrosine …

Introduction: Bright-field in situ hybridization (ISH) methods detect gene alterations that may
improve diagnostic precision and personalized management of cancer patients. Areas …

Objective In this study, we retrospectively reviewed our experience in the surgical
management of solitary fibrous tumor (SFT)/hemangiopericytomas (HPCs) of the spinal cord …

Solitary fibrous tumor (SFT) is a rare type of mesenchymal lesion with variable clinical
presentation in which specific clinicopathologic factors have been related to patient …

Background Solitary fibrous tumour (SFT) is a rare mesenchymal malignancy that lacks
robust prognostic and predictive biomarkers. Interferon-stimulated gene 15 (ISG15) is a …

The aim of this research was to evaluate the receptor tyrosine kinase inhibitor Sunitinib
combined with SN-38 in polymeric micelles for antitumor efficacy in colorectal cancer. First …

Objective: To investigate the efficacy of transcatheter arterial chemoembolization (TACE)
combined with thalidomide-mediated adjuvant therapy on the expression levels of vascular …

A solitary fibrous tumor (SFT) is a rare spindle cell tumor-derived from mesenchymal cells. It
may be linked to the fusion of the NAB2-STAT6 gene caused by 12q chromosome …

Solitary fibrous tumors (SFTs) are rare soft tissue sarcomas that rely on several epithelial–
mesenchymal transition (EMT) protein regulators for invasion/metastatic progression …

Patient-derived xenografts provide significant advantages over long-term passage cell lines
when investigating efficacy of treatments for solid tumors. Our laboratory encountered a high …