[HTML][HTML] The gut‒breast axis: programming health for life

JM Rodríguez, L Fernández, V Verhasselt - Nutrients, 2021 - mdpi.com
The gut is a pivotal organ in health and disease. The events that take place in the gut during
early life contribute to the programming, sha** and tuning of distant organs, having …

Culture models to investigate mechanisms of milk production and blood-milk barrier in mammary epithelial cells: a review and a protocol

K Kobayashi - Journal of Mammary Gland Biology and Neoplasia, 2023 - Springer
Mammary epithelial cells (MECs) are the only cell type that produces milk during lactation.
MECs also form less-permeable tight junctions (TJs) to prevent the leakage of milk and …

[HTML][HTML] Molecular mechanism of mammary gland involution: An update

MK Jena, S Jaswal, S Kumar, AK Mohanty - Developmental biology, 2019 - Elsevier
The mammary gland (MG) is a unique organ responsible for milk synthesis, secretion, and
involution to prepare the gland for subsequent lactation. The mammary epithelial cells …

Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk

AJ Twigger, LK Engelbrecht, K Bach… - Nature …, 2022 - nature.com
Under normal conditions, the most significant expansion and differentiation of the adult
mammary gland occurs in response to systemic reproductive hormones during pregnancy …

Puerarin Alleviates H2O2-Induced Oxidative Stress and Blood–Milk Barrier Impairment in Dairy Cows

C Lyu, B Yuan, Y Meng, S Cong, H Che, X Ji… - International Journal of …, 2023 - mdpi.com
During the perinatal period, the bovine mammary epithelial cells of dairy cows exhibit
vigorous metabolism and produce large amounts of reactive oxygen species (ROS). The …

[HTML][HTML] Short Chain Fatty Acids (SCFAs) Are the Potential Immunomodulatory Metabolites in Controlling Staphylococcus aureus-Mediated Mastitis

M Akhtar, SUAS Naqvi, Q Liu, H Pan, Z Ma, N Kong… - Nutrients, 2022 - mdpi.com
Mastitis is an emerging health concern in animals. An increased incidence of mastitis in
dairy cows has been reported in the last few years across the world. It is estimated that up to …

Establishment of an in vitro culture model to study milk production and the blood–milk barrier with bovine mammary epithelial cells

Y Tsugami, N Suzuki, M Kawahara… - Animal Science …, 2020 - Wiley Online Library
This study attempted to establish a culture model to recreate the milk production pathway in
bovine mammary epithelial cells (BMECs). BMECs were isolated from Holstein cows …

[HTML][HTML] Short-and long-term implications of human milk microbiota on maternal and child health

M García-Ricobaraza, JA García-Santos… - International Journal of …, 2021 - mdpi.com
Human milk (HM) is considered the most complete food for infants as its nutritional
composition is specifically designed to meet infant nutritional requirements during early life …

Valine treatment enhances antimicrobial component production in mammary epithelial cells and the milk of lactating goats without influencing the tight junction barrier

Y Tsugami, T Nii, N Isobe - Journal of Mammary Gland Biology and …, 2023 - Springer
The production of antimicrobial components and the formation of less-permeable tight
junctions (TJs) are important in the defense system of lactating mammary glands and for …

IL-1β is a key inflammatory cytokine that weakens lactation-specific tight junctions of mammary epithelial cells

K Kobayashi, K Matsunaga, Y Tsugami… - Experimental Cell …, 2021 - Elsevier
In lactating mammary glands, alveolar mammary epithelial cells (MECs) produce milk and
form less-permeable tight junctions (TJs). However, alveolar TJs are weakened with a …