The functional diversity of the mammalian intestinal microbiome far exceeds that of the host
organism, and microbial genes contribute substantially to the well-being of the host …

I. INTRODUCTION 1877 II. STUDYING THE... 1881 III. MICROBIOTA-GUT-BRAIN AXIS...
1907 IV. PATHWAYS OF COMMUNICATION 1911 V. MICROBIOTA AND SYNAPTIC... 1929 …

The gut is inhabited by a densely populated ecosystem, the gut microbiota, that is
established at birth. However, the succession by which different bacteria are incorporated …

Centenarians are an excellent model to study the relationship between the gut microbiome
and longevity. To characterize the gut microbiome signatures of aging, we conducted a …

Appreciation of the importance of the gut microbiome is growing, and it is becoming
increasingly relevant to identify preventive or therapeutic solutions targeting it. The …

The gut fungal community represents an essential element of human health, yet its
functional and metabolic potential remains insufficiently elucidated, largely due to the limited …

Malnutrition continues to threaten the lives of millions across the world, with children being
hardest hit. Although inadequate access to food and infectious disease are the primary …

Aging is characterized by the functional decline of tissues and organs and increased risk of
aging-associated disorders, which pose major societal challenges and are a public health …

Lifelong sex-and age-related trajectories of the human gut microbiota remain largely
unexplored. Using metagenomics, we derived the gut microbial composition of 2,338 adults …

Background The succession of the gut microbiota during the first few years plays a vital role
in human development. We elucidate the characteristics and alternations of the infant gut …