Role of PI3K/AKT pathway in cancer: the framework of malignant behavior
N Jiang, Q Dai, X Su, J Fu, X Feng, J Peng - Molecular biology reports, 2020 - Springer
Given that the PI3K/AKT pathway has manifested its compelling influence on multiple
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …
cellular process, we further review the roles of hyperactivation of PI3K/AKT pathway in …
Significance of miRNAs on the thyroid cancer progression and resistance to treatment with special attention to the role of cross-talk between signaling pathways
Thyroid cancer (TC) is the most prevalent endocrine malignant tumor. It has many types, the
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …
Papillary thyroid cancer (PTC)(most common and follicular thyroid carcinoma (FTC). Several …
Extracellular vesicles and particles impact the systemic landscape of cancer
Intercellular cross talk between cancer cells and stromal and immune cells is essential for
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
tumor progression and metastasis. Extracellular vesicles and particles (EVPs) are a …
MicroRNAs as the critical regulators of cell migration and invasion in thyroid cancer
Thyroid cancer (TC) is one of the most frequent endocrine malignancies that is more
common among females. Tumor recurrence is one of the most important clinical …
common among females. Tumor recurrence is one of the most important clinical …
[HTML][HTML] MiR-145: a potential biomarker of cancer migration and invasion
WX Xu, Z Liu, F Deng, DD Wang, XW Li… - American journal of …, 2019 - ncbi.nlm.nih.gov
MircoRNAs (miRNAs) are a diverse family of highly-conserved small non-coding RNAs,
which range from approximately 18 to 25 nucleotides in size. They regulate gene expression …
which range from approximately 18 to 25 nucleotides in size. They regulate gene expression …
Plasma exosomal miR-21 and miR-181a differentiates follicular from papillary thyroid cancer
R Samsonov, V Burdakov, T Shtam, Z Radzhabovа… - Tumor Biology, 2016 - Springer
Thyroid cancer (TC) is the most common endocrine malignancy and its incidence has
increased over the last few decades. As has been revealed by a number of studies, TC …
increased over the last few decades. As has been revealed by a number of studies, TC …
[HTML][HTML] Regulatory mechanisms of miR-145 expression and the importance of its function in cancer metastasis
MicroRNAs are post-transcriptional mediators of gene expression and regulation, which play
influential roles in tumorigenesis and cancer metastasis. The expression of tumor …
influential roles in tumorigenesis and cancer metastasis. The expression of tumor …
Function of microRNA-145 and mechanisms underlying its role in malignant tumor diagnosis and treatment
D Ye, Z Shen, S Zhou - Cancer management and research, 2019 - Taylor & Francis
miRNAs are single-stranded small RNAs that do not encode proteins. They can combine
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …
complementarily with the 3′-UTRs of target gene mRNA molecules to promote targeted …
[HTML][HTML] MicroRNA-145 targets MUC13 and suppresses growth and invasion of pancreatic cancer
Pancreatic cancer has a poor prognosis due to late diagnosis and ineffective therapeutic
multimodality. MUC13, a transmembrane mucin is highly involved in pancreatic cancer …
multimodality. MUC13, a transmembrane mucin is highly involved in pancreatic cancer …
Circular RNAs as the pivotal regulators of epithelial-mesenchymal transition in gastrointestinal tumor cells
Gastrointestinal (GI) cancers, as the most common human malignancies are always
considered one of the most important health challenges in the world. Late diagnosis in …
considered one of the most important health challenges in the world. Late diagnosis in …