Applications of machine learning in drug discovery and development

J Vamathevan, D Clark, P Czodrowski… - Nature reviews Drug …, 2019 - nature.com
Drug discovery and development pipelines are long, complex and depend on numerous
factors. Machine learning (ML) approaches provide a set of tools that can improve discovery …

Machine learning models for the identification of prognostic and predictive cancer biomarkers: a systematic review

Q Al-Tashi, MB Saad, A Muneer, R Qureshi… - International journal of …, 2023 - mdpi.com
The identification of biomarkers plays a crucial role in personalized medicine, both in the
clinical and research settings. However, the contrast between predictive and prognostic …

[HTML][HTML] Diagnosis of diabetes mellitus using gradient boosting machine (LightGBM)

DD Rufo, TG Debelee, A Ibenthal, WG Negera - Diagnostics, 2021 - mdpi.com
Diabetes mellitus (DM) is a severe chronic disease that affects human health and has a high
prevalence worldwide. Research has shown that half of the diabetic people throughout the …

[HTML][HTML] Artificial intelligence in pharmaceutical sciences

M Lu, J Yin, Q Zhu, G Lin, M Mou, F Liu, Z Pan, N You… - Engineering, 2023 - Elsevier
Drug discovery and development affects various aspects of human health and dramatically
impacts the pharmaceutical market. However, investments in a new drug often go …

[HTML][HTML] RN-SMOTE: Reduced Noise SMOTE based on DBSCAN for enhancing imbalanced data classification

A Arafa, N El-Fishawy, M Badawy, M Radad - Journal of King Saud …, 2022 - Elsevier
Abstract Machine learning classifiers perform well on balanced datasets. Unfortunately, a lot
of the real-world data sets are naturally imbalanced. So, imbalanced classification is a …

Towards artificial intelligence-enabled extracellular vesicle precision drug delivery

ZF Greenberg, KS Graim, M He - Advanced Drug Delivery Reviews, 2023 - Elsevier
Abstract Extracellular Vesicles (EVs), particularly exosomes, recently exploded into
nanomedicine as an emerging drug delivery approach due to their superior biocompatibility …

A systematic review of emerging feature selection optimization methods for optimal text classification: the present state and prospective opportunities

EO Abiodun, A Alabdulatif, OI Abiodun… - Neural Computing and …, 2021 - Springer
Specialized data preparation techniques, ranging from data cleaning, outlier detection,
missing value imputation, feature selection (FS), amongst others, are procedures required to …

AI-based analysis of oral lesions using novel deep convolutional neural networks for early detection of oral cancer

K Warin, W Limprasert, S Suebnukarn, S **aporntham… - Plos one, 2022 - journals.plos.org
Artificial intelligence (AI) applications in oncology have been developed rapidly with
reported successes in recent years. This work aims to evaluate the performance of deep …

Automatic classification and detection of oral cancer in photographic images using deep learning algorithms

K Warin, W Limprasert, S Suebnukarn… - Journal of Oral …, 2021 - Wiley Online Library
Background Oral cancer is a deadly disease among the most common malignant tumors
worldwide, and it has become an increasingly important public health problem in develo** …

A survey on data-driven software vulnerability assessment and prioritization

THM Le, H Chen, MA Babar - ACM Computing Surveys, 2022 - dl.acm.org
Software Vulnerabilities (SVs) are increasing in complexity and scale, posing great security
risks to many software systems. Given the limited resources in practice, SV assessment and …