Adolescence is an important ontogenetic period that is characterized by behaviors such as
enhanced novelty-seeking, impulsivity, and reward preference, which can give rise to an …

Alcohol is one of the most widely used substances. Alcohol use accounts for 5.1% of the
global disease burden, contributes substantially to societal and economic costs, and leads …

Opioid craving and relapse vulnerability is associated with severe and persistent sleep and
circadian rhythm disruptions. Understanding the neurobiological underpinnings of circadian …

Epidemiological and phenomenological studies suggest shared underpinnings between
multiple addictive behaviors. The present genetic association study was conducted as part …

Disordered eating contributes to weight gain, obesity, and type 2 diabetes (T2D), but the
precise mechanisms underlying the development of different eating patterns and connecting …

Similarities have been reported between the diagnostic and associated characteristics of
binge-eating disorder (BED) and substance-related and non-substance-related disorders …

Objective: Examine the nature of the relationship between adolescent polysubstance use
and high school noncompletion. Method: Among a sample of 9,579 adult Australian twins …

Abstract Background and aims Adolescent Binge drinking has become an increasing health
and social concern, which cause several detrimental consequences for brain integrity …

Interneurons (INs) play a crucial role in the regulation of neural activity within the medial
prefrontal cortex (mPFC), a brain region critically involved in executive functions and …

BackgroundEmerging adulthood is a peak period of risk for alcohol and illicit drug use.
Recent advances in psychiatric genetics suggest that the co-occurrence of substance use …