Dissipative structures in biological systems: bistability, oscillations, spatial patterns and waves

A Goldbeter - … Transactions of the Royal Society A …, 2018 - royalsocietypublishing.org
The goal of this review article is to assess how relevant is the concept of dissipative structure
for understanding the dynamical bases of non-equilibrium self-organization in biological …

Cytoplasmic and mitochondrial calcium signaling: a two-way relationship

B Wacquier, L Combettes… - Cold Spring Harbor …, 2019 - cshperspectives.cshlp.org
Intracellular Ca2+ signals are well organized in all cell types, and trigger a variety of vital
physiological processes. The temporal and spatial characteristics of cytosolic Ca2+ …

Collective intelligence of morphogenesis as a teleonomic process

M Levin - 2022 - osf.io
Multiscale competency is a central phenomenon in biology: molecular networks, cells,
tissues, and organisms all solve problems via behavior in various spaces (metabolic …

Fluorescent biosensor imaging meets deterministic mathematical modelling: quantitative investigation of signalling compartmentalization

C Posner, S Mehta, J Zhang - The Journal of Physiology, 2023 - Wiley Online Library
Cells execute specific responses to diverse environmental cues by encoding information in
distinctly compartmentalized biochemical signalling reactions. Genetically encoded …

[HTML][HTML] A multiscale compartment-based model of stochastic gene regulatory networks using hitting-time analysis

A Coulier, S Hellander, A Hellander - The Journal of Chemical Physics, 2021 - pubs.aip.org
Spatial stochastic models of single cell kinetics are capable of capturing both fluctuations in
molecular numbers and the spatial dependencies of the key steps of intracellular regulatory …

Signaling pathways have an inherent need for noise to acquire information

E Azpeitia, EP Balanzario, A Wagner - BMC bioinformatics, 2020 - Springer
Background All living systems acquire information about their environment. At the cellular
level, they do so through signaling pathways. Such pathways rely on reversible binding …

Signaling oscillations in embryonic development

SL Bosman, KF Sonnen - Current Topics in Developmental Biology, 2022 - Elsevier
Tight spatiotemporal control of cellular behavior and cell fate decisions is paramount to the
formation of multicellular organisms during embryonic development. Intercellular …

Insights of infected Schwann cells extinction and inherited randomness in a stochastic model of leprosy

S Ghosh, S Rana, S Mukherjee, PK Roy - Mathematical Biosciences, 2024 - Elsevier
Investigating disease progression, transmission of infection and impacts of Multidrug
Therapy (MDT) to inhibit demyelination in leprosy involves a certain amount of difficulty in …

Initial source of heterogeneity in a model for cell fate decision in the early mammalian embryo

C Robert, F Prista von Bonhorst… - Interface …, 2022 - royalsocietypublishing.org
During development, cells from a population of common progenitors evolve towards different
fates characterized by distinct levels of specific transcription factors, a process known as cell …

Analysis of nonlinear stochastic oscillations in the biochemical Goldbeter model

I Bashkirtseva, L Ryashko, S Zaitseva - Communications in Nonlinear …, 2019 - Elsevier
A noise-induced variability of nonlinear dynamics in the Goldbeter model of the enzymatic
reaction is studied. For this model, peculiarities of the stochastic behavior in the zone of …