Superoxide is a primary oxygen radical that is produced when an oxygen molecule receives
one electron. Superoxide dismutase (SOD) plays a primary role in the cellular defense …

Reactive oxygen species (ROS) are key signaling molecules that play an important role in
the progression of inflammatory disorders. An enhanced ROS generation by …

Body fat distribution is a heritable trait and a well-established predictor of adverse metabolic
outcomes, independent of overall adiposity. To increase our understanding of the genetic …

Protein post-translational modifications (PTMs) at the lysine residue, such as lysine
methylation, acetylation, and ubiquitination, are diverse, abundant, and dynamic. They play …

Maintenance of the cellular redox balance is crucial for cell survival. An increase in reactive
oxygen, nitrogen, or chlorine species can lead to oxidative stress conditions, potentially …

Abstract Aims: Hydrogen sulfide (H2S) is suggested to act as a gaseous signaling molecule
in a variety of physiological processes. Its molecular mechanism of action was proposed to …

Introduction 3. Reactive oxygen species in tumor growth and cellular survival 4. Reactive
oxygen species in cell motility and metastasis formation 5. Generation of reactive oxygen …

The tumor suppressor PTEN regulates cell migration, growth, and survival by removing the
3′-phosphate of phosphoinositides. Exposure of purified PTEN or of cells to H 2 O 2 …

Phagocytes such as neutrophils and macrophages produce reactive oxygen species (ROS)
during phagocytosis or stimulation with a wide variety of agents through activation of …

Spermatogenesis is the process by which a single spermatogonium develops into 256
spermatozoa, one of which will fertilize the ovum. Since the 1950s when the stages of the …