The oral glucose tolerance test: 100 years later

R Jagannathan, JS Neves, B Dorcely… - Diabetes, Metabolic …, 2020 - Taylor & Francis
For over 100 years, the oral glucose tolerance test (OGTT) has been the cornerstone for
detecting prediabetes and type 2 diabetes (T2DM). In recent decades, controversies have …

Review of methods for detecting glycemic disorders

M Bergman, M Abdul-Ghani, RA DeFronzo… - Diabetes research and …, 2020 - Elsevier
Prediabetes (intermediate hyperglycemia) consists of two abnormalities, impaired fasting
glucose (IFG) and impaired glucose tolerance (IGT) detected by a standardized 75-gram …

[HTML][HTML] Oral glucose tolerance test in diabetes, the old method revisited

FY Kuo, KC Cheng, Y Li, JT Cheng - World journal of diabetes, 2021 - ncbi.nlm.nih.gov
The oral glucose tolerance test (OGTT) has been widely used both in clinics and in basic
research for a long time. It is applied to diagnose impaired glucose tolerance and/or type 2 …

Time to glucose peak during an oral glucose tolerance test identifies prediabetes risk

ST Chung, J Ha, AU Onuzuruike, K Kasturi… - Clinical …, 2017 - Wiley Online Library
Context Morphological characteristics of the glucose curve during an oral glucose tolerance
test (OGTT)(time to peak and shape) may reflect different phenotypes of insulin secretion …

Pathophysiological characteristics underlying different glucose response curves: a latent class trajectory analysis from the prospective EGIR-RISC study

A Hulman, DR Witte, D Vistisen, B Balkau… - Diabetes …, 2018 - Am Diabetes Assoc
OBJECTIVE Glucose measurements during an oral glucose tolerance test (OGTT) are useful
in predicting diabetes and its complications. However, knowledge of the pathophysiology …

Glucose patterns during an oral glucose tolerance test and associations with future diabetes, cardiovascular disease and all-cause mortality rate

A Hulman, D Vistisen, C Glümer, M Bergman, DR Witte… - Diabetologia, 2018 - Springer
Aims/hypothesis In addition to blood glucose concentrations measured in the fasting state
and 2 h after an OGTT, intermediate measures during an OGTT may provide additional …

Stratification of type 2 diabetes based on routine clinical markers

N Safai, A Ali, P Rossing, M Ridderstråle - Diabetes research and clinical …, 2018 - Elsevier
Aims We hypothesized that patients with dysregulated type 2 diabetes may be stratified
based on routine clinical markers. Methods In this retrospective cohort study, diabetes …

The oral glucose tolerance test-derived incremental glucose peak is associated with greater arterial stiffness and maladaptive arterial remodeling: the Maastricht Study

YD Foreman, MCGJ Brouwers… - Cardiovascular …, 2019 - Springer
Background Daily glucose variability may contribute to vascular complication development
irrespective of mean glucose values. The incremental glucose peak (IGP) during an oral …

Mechanistic insights into the heterogeneity of glucose response classes in youths with obesity: a latent class trajectory approach

D Tricò, S McCollum, S Samuels, N Santoro… - Diabetes …, 2022 - Am Diabetes Assoc
OBJECTIVE In a large, multiethnic cohort of youths with obesity, we analyzed
pathophysiological and genetic mechanisms underlying variations in plasma glucose …

Different physiological mechanisms underlie an adverse cardiovascular disease risk profile in men and women

A Fappi, B Mittendorfer - Proceedings of the Nutrition Society, 2020 - cambridge.org
CVD affect about one-third of the population and are the leading cause of mortality. The
prevalence of CVD is closely linked to the prevalence of obesity because obesity is …