Coma and consciousness: paradigms (re) framed by neuroimaging

S Laureys, ND Schiff - Neuroimage, 2012 - Elsevier
The past 15years have provided an unprecedented collection of discoveries that bear upon
our scientific understanding of recovery of consciousness in the human brain following …

Recent advances in disorders of consciousness: focus on the diagnosis

O Gosseries, ND Zasler, S Laureys - Brain injury, 2014 - Taylor & Francis
Background: Over the last two decades, there has been a considerable increase in
knowledge of brain function in patients with disorders of consciousness following a coma …

Intrinsic functional connectivity differentiates minimally conscious from unresponsive patients

A Demertzi, G Antonopoulos, L Heine, HU Voss… - Brain, 2015 - academic.oup.com
Despite advances in resting state functional magnetic resonance imaging investigations,
clinicians remain with the challenge of how to implement this paradigm on an individualized …

A role for the default mode network in the bases of disorders of consciousness

D Fernández‐Espejo, A Soddu, D Cruse… - Annals of …, 2012 - Wiley Online Library
Objective: Functional connectivity in the default mode network (DMN) is known to be
reduced in patients with disorders of consciousness, to a different extent depending on their …

The ascending reticular activating system from pontine reticular formation to the thalamus in the human brain

SS Yeo, PH Chang, SH Jang - Frontiers in human neuroscience, 2013 - frontiersin.org
Introduction: Action of the ascending reticular activating system (ARAS) on the cerebral
cortex is responsible for achievement of consciousness. In this study, we attempted to …

[HTML][HTML] Altered network properties of the fronto-parietal network and the thalamus in impaired consciousness

JS Crone, A Soddu, Y Höller, A Vanhaudenhuyse… - NeuroImage: Clinical, 2014 - Elsevier
Recovery of consciousness has been associated with connectivity in the frontal cortex and
parietal regions modulated by the thalamus. To examine this model and to relate alterations …

[HTML][HTML] Impaired consciousness is linked to changes in effective connectivity of the posterior cingulate cortex within the default mode network

JS Crone, M Schurz, Y Höller, J Bergmann, M Monti… - Neuroimage, 2015 - Elsevier
The intrinsic connectivity of the default mode network has been associated with the level of
consciousness in patients with severe brain injury. Especially medial parietal regions are …

Deactivation of the default mode network as a marker of impaired consciousness: an fMRI study

JS Crone, G Ladurner, Y Höller, S Golaszewski… - PloS one, 2011 - journals.plos.org
Diagnosis of patients with a disorder of consciousness is very challenging. Previous studies
investigating resting state networks demonstrate that 2 main features of the so-called default …

Deep brain stimulation improves electroencephalogram functional connectivity of patients with minimally conscious state

Y Dang, Y Wang, X **a, Y Yang, Y Bai… - CNS neuroscience & …, 2023 - Wiley Online Library
Aim Deep brain stimulation (DBS) is a potential neuromodulatory therapy that enhances
recovery from disorders of consciousness, especially minimally conscious state (MCS). This …

Multiple tasks and neuroimaging modalities increase the likelihood of detecting covert awareness in patients with disorders of consciousness

RM Gibson, D Fernández-Espejo… - Frontiers in Human …, 2014 - frontiersin.org
Minimal or inconsistent behavioral responses to command make it challenging to accurately
diagnose the level of awareness of a patient with a Disorder of consciousness (DOC). By …