Animal venoms are complex mixtures containing peptides and proteins known as toxins,
which are responsible for the deleterious effect of envenomations. Across the animal …

The gasdermin family of pore-forming proteins (PFPs) has recently emerged as key
molecular players controlling immune-related cell death in mammals. Characterized …

The potent neurotoxic venom of the black widow spider contains a cocktail of seven phylum-
specific latrotoxins (LTXs), but only one, α-LTX, targets vertebrates. This 130 kDa toxin binds …

Pore-forming proteins (PFPs) play a central role in many biological processes related to
infection, immunity, cancer, and neurodegeneration. A common feature of PFPs is their …

The sea represents a major source of biodiversity. It exhibits many different ecosystems in a
huge variety of environmental conditions where marine organisms have evolved with …

Envenomation by the Indian ornamental tarantula (Poecilotheria regalis) is medically
relevant to humans, both in its native India and worldwide, where they are kept as pets …

Enabling control over the bioactivity of proteins with light, along with the principles of
photopharmacology, has the potential to generate safe and targeted medical treatments …

Venoms constitute complex mixtures of many different molecules arising from evolution in
processes driven by continuous prey–predator interactions. One of the most common …

Immunotoxins are chimeric molecules that combine the specificity of an antibody to
recognize and bind tumor antigens with the potency of the enzymatic activity of a toxin, thus …

Naturally derived antimicrobial peptides have been an area of great interest because of high
selectivity against bacterial targets over host cells and the limited development of bacterial …