The incidence of inflammatory bowel diseases (IBD) emerged with Westernisation of dietary
habits worldwide. Crohn's disease and ulcerative colitis are chronic debilitating conditions …

S100A8 and S100A9 (also known as MRP8 and MRP14, respectively) are Ca2+ binding
proteins belonging to the S100 family. They often exist in the form of heterodimer, while …

The S100 proteins, a family of calcium-binding cytosolic proteins, have a broad range of
intracellular and extracellular functions through regulating calcium balance, cell apoptosis …

Neutrophils and macrophages are critical to the innate immune response, but cooperative
mechanisms used by these cells to combat extracellular pathogens are not well understood …

Scavenger receptors belong to a superfamily of proteins that are structurally heterogeneous
and encompass the miscellaneous group of transmembrane proteins and soluble secretory …

The S100 protein family consists of 24 members functionally distributed into three main
subgroups: those that only exert intracellular regulatory effects, those with intracellular and …

CD146 was originally identified as a melanoma cell adhesion molecule (MCAM) and highly
expressed in many tumors and endothelial cells. However, the evidence that CD146 acts as …

Abstract In 1994, the “danger model” argued that adaptive immune responses are driven
rather by molecules released upon tissue damage than by the recognition of “strange” …

Abstract Background Calprotectin (S100A8/S100A9), a heterodimeric EF-hand Ca 2+
binding protein, are abundant in cytosol of neutrophils and are involved in inflammatory …

The receptor for advanced glycation end-product (RAGE) is the signal transduction receptor
which senses a variety of signalling molecules including advanced glycation end products …