Neuroinflammation and depression: A review

R Troubat, P Barone, S Leman… - European journal of …, 2021 - Wiley Online Library
Some recent clinical and preclinical evidence suggests that neuroinflammation is a key
factor that interacts with the three neurobiological correlates of major depressive disorder …

Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for mood disorders

GS Malhi, D Bassett, P Boyce… - Australian & New …, 2015 - journals.sagepub.com
Objectives: To provide guidance for the management of mood disorders, based on scientific
evidence supplemented by expert clinical consensus and formulate recommendations to …

The dopamine hypothesis of bipolar affective disorder: the state of the art and implications for treatment

AH Ashok, TR Marques, S Jauhar, MM Nour… - Molecular …, 2017 - nature.com
Bipolar affective disorder is a common neuropsychiatric disorder. Although its
neurobiological underpinnings are incompletely understood, the dopamine hypothesis has …

Inhibitors of MAO-A and MAO-B in psychiatry and neurology

JPM Finberg, JM Rabey - Frontiers in pharmacology, 2016 - frontiersin.org
Inhibitors of MAO-A and MAO-B are in clinical use for the treatment of psychiatric and
neurological disorders respectively. Elucidation of the molecular structure of the active sites …

A brief history of the development of antidepressant drugs: from monoamines to glutamate.

TM Hillhouse, JH Porter - Experimental and clinical …, 2015 - psycnet.apa.org
Major depressive disorder (MDD) is a chronic, recurring, and debilitating mental illness that
is the most common mood disorder in the United States. It has been almost 50 years since …

Design, synthesis, and biological activity of dual monoamine oxidase A and heat shock protein 90 inhibitors, N-Methylpropargylamine-conjugated 4 …

HJ Tseng, S Banerjee, B Qian, MJ Lai, TY Wu… - European Journal of …, 2023 - Elsevier
Abstract Monoamine oxidase A (MAO A) and heat shock protein 90 (HSP90) inhibitors have
been shown to decrease the progression of glioblastoma (GBM) and other cancers. In this …

Neuroinflammation, memory, and depression: new approaches to hippocampal neurogenesis

A Wu, J Zhang - Journal of Neuroinflammation, 2023 - Springer
As one of most common and severe mental disorders, major depressive disorder (MDD)
significantly increases the risks of premature death and other medical conditions for patients …

Monoamine oxidase B inhibitors in Parkinson's disease

L Dezsi, L Vecsei - … (Formerly Current Drug Targets-CNS & …, 2017 - ingentaconnect.com
Background: Parkinson's disease (PD) is a neurodegenerative disorder with a prevalence
increasing with age. Oxidative stress and glutamate toxicity are involved in its …

[HTML][HTML] The poly (I: C)-induced maternal immune activation model in preclinical neuropsychiatric drug discovery

S Reisinger, D Khan, E Kong, A Berger, A Pollak… - Pharmacology & …, 2015 - Elsevier
Increasing epidemiological and experimental evidence implicates gestational infections as
one important factor involved in the pathogenesis of several neuropsychiatric disorders …

Neurobiology of depression in Parkinson's disease: Insights into epidemiology, molecular mechanisms and treatment strategies

MH Ahmad, MA Rizvi, M Ali, AC Mondal - Ageing research reviews, 2023 - Elsevier
Parkinson's disease (PD) is characterized mainly by motor dysfunctions due to the
progressive loss of dopaminergic neurons. However, PD patients experience a multitude of …