The evolution of IgE in mammals added an extra layer of immune protection at body
surfaces to provide a rapid and local response against antigens from the environment. The …

The Epstein-Barr virus (EBV) is a ubiquitous human pathogen linked to various diseases,
including infectious mononucleosis and multiple types of cancer. To control and eliminate …

The complement system is an essential part of innate immunity, typically conferring
protection via eliminating pathogens and accumulating debris. However, the defensive …

Age-related macular degeneration (AMD) remains a major cause of legal blindness, and
treatment for the geographic atrophy form of AMD is a significant unmet need. Dysregulation …

The complement system has been involved in the pathogenesis of multiple
neuroinflammatory and neurodegenerative conditions. In this review, we evaluated the …

Metachromatic leukodystrophy (MLD) is an autosomal recessively inherited metabolic
disease characterized by deficient activity of the lysosomal enzyme arylsulfatase A. Its …

The advent of single-cell multi-omics sequencing technology makes it possible for
researchers to leverage multiple modalities for individual cells and explore cell …

The complement activation system plays important roles to maintain homeostasis in the host
and to fight foreign invaders to protect the host. Therefore, the complement system is …

This research dives into the intricate immune landscape of head and neck cancer (HNC),
with a keen focus on the roles of specific immune cell subpopulations and their linked …

Background Preterm birth and its complications are the primary cause of death among
children under the age of 5. Among the survivors, morbidity both perinatally and later in life …