Vitamin D is unique in being generated in our skin following ultraviolet radiation (UVR)
exposure. Ongoing research into vitamin D must therefore always consider the influence of …

This review examines putative, yet likely critical evolutionary pressures contributing to
human skin pigmentation and subsequently, depigmentation phenotypes. To achieve this, it …

Objective To test the “vitamin D‐folate hypothesis for the evolution of human skin
pigmentation.” Methods Total ozone map** spectrometer (TOMS) satellite data were used …

This review explores contemporary ideas about the relationship between light exposure and
vitamin biology. Nutritional biochemistry has long recognized the relationship between …

Objectives Folate‐mediated 1‐carbon transfer processes are vital in human health but are
susceptible to independent and interactive influences of genetic variance and environmental …

Background Key reactions in folate-mediated single-carbon metabolism are regulated by
folate cycle enzymes. Violations of the folate cycle may be associated with the occurrence of …

The conventional view of vitamins reflects a diverse group of small molecules that facilitate
critical aspects of metabolism and prevent potentially fatal deficiency syndromes. However …

Elevated homocysteine (Hcy) levels are a risk factor for vascular diseases. Recently,
increases in ultraviolet radiation (UVR) have been linked to decreased Hcy levels. This …

Folate has been proposed to be an efficacious treatment strategy for depression. The
mandatory fortification of flour with synthetic folic acid (FA) in over 80 countries has yielded …

Adequate levels of folate are crucial for human development. MTHFR (Methylene
tetrahydrofolate reductase) is involved in the metabolism of folic acid and other B vitamins …