Chemosensory signal transduction in Caenorhabditis elegans

DM Ferkey, P Sengupta, ND L'Etoile - Genetics, 2021 - academic.oup.com
Chemosensory neurons translate perception of external chemical cues, including odorants,
tastants, and pheromones, into information that drives attraction or avoidance motor …

Males, Outcrossing, and Sexual Selection in Caenorhabditis Nematodes

AD Cutter, LT Morran, PC Phillips - Genetics, 2019 - academic.oup.com
Males of Caenorhabditis elegans provide a crucial practical tool in the laboratory, but, as the
rarer and more finicky sex, have not enjoyed the same depth of research attention as …

Transgenerational inheritance of sexual attractiveness via small RNAs enhances evolvability in C. elegans

IA Toker, I Lev, Y Mor, Y Gurevich, D Fisher… - Developmental Cell, 2022 - cell.com
It is unknown whether transient transgenerational epigenetic responses to environmental
challenges affect the process of evolution, which typically unfolds over many generations …

Pathogenic bacteria modulate pheromone response to promote mating

T Wu, M Ge, M Wu, F Duan, J Liang, M Chen… - Nature, 2023 - nature.com
Pathogens generate ubiquitous selective pressures and host–pathogen interactions alter
social behaviours in many animals,,–. However, very little is known about the neuronal …

Reprogramming the topology of the nociceptive circuit in C. elegans reshapes sexual behavior

V Pechuk, G Goldman, Y Salzberg, AH Chaubey… - Current biology, 2022 - cell.com
The effect of the detailed connectivity of a neural circuit on its function and the resulting
behavior of the organism is a key question in many neural systems. Here, we study the …

C. elegans males optimize mate-preference decisions via sex-specific responses to multimodal sensory cues

J Luo, C Bainbridge, RM Miller, A Barrios, DS Portman - Current Biology, 2024 - cell.com
For sexually reproducing animals, selecting optimal mates is important for maximizing
reproductive fitness. In the nematode C. elegans, populations reproduce largely by …

Functional imaging and quantification of multineuronal olfactory responses in C. elegans

A Lin, S Qin, H Casademunt, M Wu, W Hung… - Science …, 2023 - science.org
Many animals perceive odorant molecules by collecting information from ensembles of
olfactory neurons, where each neuron uses receptors that are tuned to recognize certain …

The Makorin lep-2 and the lncRNA lep-5 regulate lin-28 to schedule sexual maturation of the C. elegans nervous system

H Lawson, E Vuong, RM Miller, K Kiontke, DHA Fitch… - Elife, 2019 - elifesciences.org
Sexual maturation must occur on a controlled developmental schedule. In mammals,
Makorin3 (MKRN3) and the miRNA regulators LIN28A/B are key regulators of this process …

A sex-specific switch in a single glial cell patterns the apical extracellular matrix

W Fung, TM Tan, I Kolotuev, MG Heiman - Current Biology, 2023 - cell.com
Apical extracellular matrix (aECM) constitutes the interface between every tissue and the
outside world. It is patterned into diverse tissue-specific structures through unknown …

Direct glia-to-neuron transdifferentiation gives rise to a pair of male-specific neurons that ensure nimble male mating

L Molina-García, C Lloret-Fernández, SJ Cook, B Kim… - Elife, 2020 - elifesciences.org
Sexually dimorphic behaviours require underlying differences in the nervous system
between males and females. The extent to which nervous systems are sexually dimorphic …