Applications of deep learning techniques for automated multiple sclerosis detection using magnetic resonance imaging: A review

A Shoeibi, M Khodatars, M Jafari, P Moridian… - Computers in Biology …, 2021 - Elsevier
Multiple Sclerosis (MS) is a type of brain disease which causes visual, sensory, and motor
problems for people with a detrimental effect on the functioning of the nervous system. In …

Machine learning for brain age prediction: Introduction to methods and clinical applications

L Baecker, R Garcia-Dias, S Vieira, C Scarpazza… - …, 2021 - thelancet.com
The rise of machine learning has unlocked new ways of analysing structural neuroimaging
data, including brain age prediction. In this state-of-the-art review, we provide an …

Mind the gap: Performance metric evaluation in brain‐age prediction

AMG de Lange, M Anatürk, J Rokicki… - Human Brain …, 2022 - Wiley Online Library
Estimating age based on neuroimaging‐derived data has become a popular approach to
develo** markers for brain integrity and health. While a variety of machine‐learning …

[HTML][HTML] Deep neural networks learn general and clinically relevant representations of the ageing brain

EH Leonardsen, H Peng, T Kaufmann, I Agartz… - NeuroImage, 2022 - Elsevier
The discrepancy between chronological age and the apparent age of the brain based on
neuroimaging data—the brain age delta—has emerged as a reliable marker of brain health …

Factors associated with brain ageing-a systematic review

J Wrigglesworth, P Ward, IH Harding, D Nilaweera… - BMC neurology, 2021 - Springer
Background Brain age is a biomarker that predicts chronological age using neuroimaging
features. Deviations of this predicted age from chronological age is considered a sign of age …

Longitudinal assessment of multiple sclerosis with the brain‐age paradigm

JH Cole, J Raffel, T Friede, A Eshaghi… - Annals of …, 2020 - Wiley Online Library
Objective During the natural course of multiple sclerosis (MS), the brain is exposed to aging
as well as disease effects. Brain aging can be modeled statistically; the so‐called “brain …

[HTML][HTML] Multimodal brain-age prediction and cardiovascular risk: The Whitehall II MRI sub-study

AMG De Lange, M Anatürk, S Suri, T Kaufmann… - NeuroImage, 2020 - Elsevier
Brain age is becoming a widely applied imaging-based biomarker of neural aging and
potential proxy for brain integrity and health. We estimated multimodal and modality-specific …

[HTML][HTML] Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

ED Sun, OY Zhou, M Hauptschein, N Rappoport, L Xu… - Nature, 2024 - nature.com
Old age is associated with a decline in cognitive function and an increase in
neurodegenerative disease risk. Brain ageing is complex and is accompanied by many …

Cardiometabolic risk factors associated with brain age and accelerated brain ageing

D Beck, AMG de Lange, ML Pedersen… - Human brain …, 2022 - Wiley Online Library
The structure and integrity of the ageing brain is interchangeably linked to physical health,
and cardiometabolic risk factors (CMRs) are associated with dementia and other brain …

Brain age prediction: A comparison between machine learning models using brain morphometric data

J Han, SY Kim, J Lee, WH Lee - Sensors, 2022 - mdpi.com
Brain structural morphology varies over the aging trajectory, and the prediction of a person's
age using brain morphological features can help the detection of an abnormal aging …