Ultra-high-performance liquid chromatography high-resolution mass spectrometry variants for metabolomics research

L Perez de Souza, S Alseekh, F Scossa, AR Fernie - Nature Methods, 2021 - nature.com
Ultra-high-performance liquid chromatography high-resolution mass spectrometry (UHPLC–
HRMS) variants currently represent the best tools to tackle the challenges of complexity and …

Tomato fruit development and metabolism

M Quinet, T Angosto, FJ Yuste-Lisbona… - Frontiers in plant …, 2019 - frontiersin.org
Tomato (Solanum lycopersicum L.) belongs to the Solanaceae family and is the second
most important fruit or vegetable crop next to potato (Solanum tuberosum L.). It is cultivated …

Graph pangenome captures missing heritability and empowers tomato breeding

Y Zhou, Z Zhang, Z Bao, H Li, Y Lyu, Y Zan, Y Wu… - Nature, 2022 - nature.com
Missing heritability in genome-wide association studies defines a major problem in genetic
analyses of complex biological traits,. The solution to this problem is to identify all causal …

Super-pangenome analyses highlight genomic diversity and structural variation across wild and cultivated tomato species

N Li, Q He, J Wang, B Wang, J Zhao, S Huang… - Nature Genetics, 2023 - nature.com
Effective utilization of wild relatives is key to overcoming challenges in genetic improvement
of cultivated tomato, which has a narrow genetic basis; however, current efforts to decipher …

Major impacts of widespread structural variation on gene expression and crop improvement in tomato

M Alonge, X Wang, M Benoit, S Soyk, L Pereira… - Cell, 2020 - cell.com
Structural variants (SVs) underlie important crop improvement and domestication traits.
However, resolving the extent, diversity, and quantitative impact of SVs has been …

The tomato pan-genome uncovers new genes and a rare allele regulating fruit flavor

L Gao, I Gonda, H Sun, Q Ma, K Bao, DM Tieman… - Nature …, 2019 - nature.com
Modern tomatoes have narrow genetic diversity limiting their improvement potential. We
present a tomato pan-genome constructed using genome sequences of 725 …

RaGOO: fast and accurate reference-guided scaffolding of draft genomes

M Alonge, S Soyk, S Ramakrishnan, X Wang… - Genome biology, 2019 - Springer
We present RaGOO, a reference-guided contig ordering and orienting tool that leverages
the speed and sensitivity of Minimap2 to accurately achieve chromosome-scale assemblies …

Metabolomics-centered mining of plant metabolic diversity and function: Past decade and future perspectives

S Shen, C Zhan, C Yang, AR Fernie, J Luo - Molecular Plant, 2023 - cell.com
Plants are natural experts in organic synthesis, being able to generate large numbers of
specific metabolites with widely varying structures that help them adapt to variable survival …

Recent advances in the application of metabolomics for food safety control and food quality analyses

S Li, Y Tian, P Jiang, Y Lin, X Liu… - Critical reviews in food …, 2021 - Taylor & Francis
As one of the omics fields, metabolomics has unique advantages in facilitating the
understanding of physiological and pathological activities in biology, physiology, pathology …

De novo domestication: an alternative route toward new crops for the future

AR Fernie, J Yan - Molecular plant, 2019 - cell.com
Current global agricultural production must feed over 7 billion people. However, productivity
varies greatly across the globe and is under threat from both increased competitions for land …