This review summarizes current knowledge about the mechanisms of timely binding and
dissociation of two nucleoid proteins, IHF and Fis, which play fundamental roles in the …

Highlights•Nucleoprotein structures are part of the extracellular matrix of biofilms.•The
nucleoprotein structures of biofilms are ubiquitous.•The nucleoprotein structures are both for …

For DNA replication initiation in Bacteria, replication initiation proteins bind to double-
stranded DNA (dsDNA) and interact with single-stranded DNA (ssDNA) at the replication …

The DnaA protein has long been considered to play the key role in the initiation of
chromosome replication in modern bacteria. Many questions about this role, however …

A fundamental problem in biology is how cells obtain the reproducible, coherent phenotypes
needed for natural selection to act or, put differently, how cells manage to limit their …

Oscillation of the active form of the initiator protein DnaA (ATP-DnaA) allows for the timely
regulation for chromosome replication. After initiation, DnaA-bound ATP is hydrolyzed …

Timely initiation of chromosomal DNA replication in Escherichia coli is achieved by cell cycle-
coordinated regulation of the replication origin, oriC, and the replication initiator, ATP-DnaA …

Although the mechanism of DNA replication initiation has been investigated for over 50
years, many important discoveries have been made related to this process in recent years …

For bidirectional replication in Escherichia coli, higher order complexes are formed at the
replication origin oriC by the initiator protein DnaA, which locally unwinds the left edge of …

The ability to initiate DNA replication is a critical step in the proliferation of all organisms. In
bacteria, this process is mediated by an ATP‐dependent replication initiator protein, DnaA …