Overlap** genes in natural and engineered genomes
Modern genome-scale methods that identify new genes, such as proteogenomics and
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …
ribosome profiling, have revealed, to the surprise of many, that overlap in genes, open …
Human papillomavirus genomics: Understanding carcinogenicity
Human papillomavirus (HPV) causes virtually all cervical cancers and many cancers at other
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
anatomical sites in both men and women. However, only 12 of 448 known HPV types are …
Dynamically evolving novel overlap** gene as a factor in the SARS-CoV-2 pandemic
Understanding the emergence of novel viruses requires an accurate and comprehensive
annotation of their genomes. Overlap** genes (OLGs) are common in viruses and have …
annotation of their genomes. Overlap** genes (OLGs) are common in viruses and have …
Transmission dynamics of SARS-CoV-2 within-host diversity in two major hospital outbreaks in South Africa
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes acute, highly
transmissible respiratory infection in humans and a wide range of animal species. Its rapid …
transmissible respiratory infection in humans and a wide range of animal species. Its rapid …
Origin, evolution and stability of overlap** genes in viruses: a systematic review
A Pavesi - Genes, 2021 - mdpi.com
During their long evolutionary history viruses generated many proteins de novo by a
mechanism called “overprinting”. Overprinting is a process in which critical nucleotide …
mechanism called “overprinting”. Overprinting is a process in which critical nucleotide …
Are antisense proteins in prokaryotes functional?
Many prokaryotic RNAs are transcribed from loci outside of annotated protein coding genes.
Across bacterial species hundreds of short open reading frames antisense to annotated …
Across bacterial species hundreds of short open reading frames antisense to annotated …
HIV-1 natural antisense transcription and its role in viral persistence
Natural antisense transcripts (NATs) represent a class of RNA molecules that are
transcribed from the opposite strand of a protein-coding gene, and that have the ability to …
transcribed from the opposite strand of a protein-coding gene, and that have the ability to …
Joint host-pathogen genomic analysis identifies hepatitis B virus mutations associated with human NTCP and HLA class I variation
Evolutionary changes in the hepatitis B virus (HBV) genome could reflect its adaptation to
host-induced selective pressure. Leveraging paired human exome and ultra-deep HBV …
host-induced selective pressure. Leveraging paired human exome and ultra-deep HBV …
Spotlight on alternative frame coding: Two long overlap** genes in Pseudomonas aeruginosa are translated and under purifying selection
The existence of overlap** genes (OLGs) with significant coding overlaps revolutionizes
our understanding of genomic complexity. We report two exceptionally long (957 nt and …
our understanding of genomic complexity. We report two exceptionally long (957 nt and …
The HIV-1 antisense gene ASP: the new kid on the block
Viruses have developed incredibly creative ways of making a virtue out of necessity,
including taking full advantage of their small genomes. Indeed, viruses often encode …
including taking full advantage of their small genomes. Indeed, viruses often encode …