Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Chalcones, containing an α, β-unsaturated ketone fragment, are an important
pharmacologically active agents because of their diverse mechanisms. This review provides …

Staphylococcus aureus can readily form biofilm which enhances the drug-resistance,
resulting in life-threatening infections involving different organs. Biofilm formation occurs due …

The prevalence of antimicrobial-resistant pathogens significantly limited the number of
effective antibiotics available clinically, which urgently requires new drug targets to screen …

Implant-associated infections (IAIs) caused by S. aureus can result in serious challenges
after orthopedic surgery. Due to biofilm formation and antibiotic resistance, this refractory …

Antimicrobial resistance has posed a serious health concern worldwide, which is mainly due
to the excessive use of antibiotics. In this study, gold nanoparticles synthesized from the …

Methicillin‐resistant Staphylococcus aureus (MRSA) causes diseases ranging from skin
infections to lethal sepsis and has become a serious threat to human health due to multiple …

The emergence of bactericidal antibiotic-resistant strains has increased the demand for
alternative therapeutic agents, such as antivirulence agents targeting the virulence …

Chalcones are flavonoid-related aromatic ketones and enones generated from plants. The
chalcones have a wide range of biological activities, such as anti-tumor, calming, and …

Bacterial histidine kinase (BHK) is a constituent of the two-component signaling (TCS)
pathway, which is responsible for the regulation of a number of processes connected to …