Molecular responses to acute exercise and their relevance for adaptations in skeletal muscle to exercise training
Repeated, episodic bouts of skeletal muscle contraction undertaken frequently as structured
exercise training are a potent stimulus for physiological adaptation in many organs …
exercise training are a potent stimulus for physiological adaptation in many organs …
Exercise metabolism and adaptation in skeletal muscle
Viewing metabolism through the lens of exercise biology has proven an accessible and
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …
practical strategy to gain new insights into local and systemic metabolic regulation. Recent …
Mechanisms of mechanical overload-induced skeletal muscle hypertrophy: current understanding and future directions
Mechanisms underlying mechanical overload-induced skeletal muscle hypertrophy have
been extensively researched since the landmark report by Morpurgo (1897) of “work …
been extensively researched since the landmark report by Morpurgo (1897) of “work …
[HTML][HTML] An Evidence-Based Narrative Review of Mechanisms of Resistance Exercise–Induced Human Skeletal Muscle Hypertrophy
Skeletal muscle plays a critical role in physical function and metabolic health. Muscle is a
highly adaptable tissue that responds to resistance exercise (RE; loading) by …
highly adaptable tissue that responds to resistance exercise (RE; loading) by …
Nucleus type-specific DNA methylomics reveals epigenetic “memory” of prior adaptation in skeletal muscle
Using a mouse model of conditional and inducible in vivo fluorescent myonuclear labeling
(HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite …
(HSA-GFP), sorting purification of nuclei, low-input reduced representation bisulfite …
Late‐life exercise mitigates skeletal muscle epigenetic aging
There are functional benefits to exercise in muscle, even when performed late in life, but the
contributions of epigenetic factors to late‐life exercise adaptation are poorly defined. Using …
contributions of epigenetic factors to late‐life exercise adaptation are poorly defined. Using …
Multi-transcriptome analysis following an acute skeletal muscle growth stimulus yields tools for discerning global and MYC regulatory networks
Myc is a powerful transcription factor implicated in epigenetic reprogramming, cellular
plasticity, and rapid growth as well as tumorigenesis. Cancer in skeletal muscle is extremely …
plasticity, and rapid growth as well as tumorigenesis. Cancer in skeletal muscle is extremely …
Muscle-specific cellular and molecular adaptations to late-life voluntary concurrent exercise
Murine exercise models can provide information on factors that influence muscle
adaptability with aging, but few translatable solutions exist. Progressive weighted wheel …
adaptability with aging, but few translatable solutions exist. Progressive weighted wheel …
A molecular signature defining exercise adaptation with ageing and in vivo partial reprogramming in skeletal muscle
Exercise promotes functional improvements in aged tissues, but the extent to which it
simulates partial molecular reprogramming is unknown. Using transcriptome profiling from …
simulates partial molecular reprogramming is unknown. Using transcriptome profiling from …
Impact of physical activity and exercise on the epigenome in skeletal muscle and effects on systemic metabolism
Exercise and physical activity induces physiological responses in organisms, and
adaptations in skeletal muscle, which is beneficial for maintaining health and preventing …
adaptations in skeletal muscle, which is beneficial for maintaining health and preventing …