Antibacterial nanomaterials: mechanisms, impacts on antimicrobial resistance and design principles

M **e, M Gao, Y Yun, M Malmsten… - Angewandte Chemie …, 2023 - Wiley Online Library
Antimicrobial resistance (AMR) is one of the biggest threats to the environment and health.
AMR rapidly invalidates conventional antibiotics, and antimicrobial nanomaterials have …

Nanotechnology as a promising approach to combat multidrug resistant bacteria: a comprehensive review and future perspectives

HF Hetta, YN Ramadan, AI Al-Harbi, E A. Ahmed… - Biomedicines, 2023 - mdpi.com
The wide spread of antibiotic resistance has been alarming in recent years and poses a
serious global hazard to public health as it leads to millions of deaths all over the world. The …

Impacts of temperatures and phosphoric-acid modification to the physicochemical properties of biochar for excellent sulfadiazine adsorption

XY Zeng, Y Wang, RX Li, HL Cao, YF Li, J Lü - Biochar, 2022 - Springer
The textural properties and surface chemistry of phosphoric acid-modified biochars (PABCs)
prepared at different pyrolysis temperatures (500–700° C) were studied based on the results …

Molecular mechanism of plasmid-borne resistance to sulfonamide antibiotics

M Venkatesan, M Fruci, LA Verellen, T Skarina… - Nature …, 2023 - nature.com
The sulfonamides (sulfas) are the oldest class of antibacterial drugs and inhibit the bacterial
dihydropteroate synthase (DHPS, encoded by folP), through chemical mimicry of its co …

Modified chitosan: insight on biomedical and industrial applications

GI Edo, E Yousif, MH Al-Mashhadani - International Journal of Biological …, 2024 - Elsevier
Abstract Chitosan (CS), a by–product of chitin deacetylation can be useful in a broad range
of purposes, to mention agriculture, pharmaceuticals, material science, food and nutrition …

Promoting the suitability of graphitic bio-carbon nitride and metal oxide nanoparticles: A review of sulfonamides photocatalytic degradation

ZU Zango, MA Lawal, F Usman, A Sulieman, H Akhdar… - Chemosphere, 2024 - Elsevier
The widespread consumption of pharmaceutical drugs and their incomplete breakdown in
organisms has led to their extensive presence in aquatic environments. The indiscriminate …

Current scenario of quinolone hybrids with potential antibacterial activity against ESKAPE pathogens

J Gao, H Hou, F Gao - European Journal of Medicinal Chemistry, 2023 - Elsevier
Abstract The ESKAPE (Escherichia coli/E. coli, Staphylococcus aureus/S. aureus, Klebsiella
pneumonia/K. pneumoniae, Acinetobacter Baumannii/A. baumannii, Pseudomonas …

Photo‐and Cobalt‐Catalyzed Synthesis of Heterocycles via Cycloisomerization of Unactivated Olefins

H Lindner, WM Amberg, T Martini… - Angewandte Chemie …, 2024 - Wiley Online Library
We report a general, intramolecular cycloisomerization of unactivated olefins with pendant
nucleophiles. The reaction proceeds under mild conditions and tolerates ethers, esters …

FDA-approved small molecules in 2022: Clinical uses and their synthesis

D Benedetto Tiz, L Bagnoli, O Rosati, F Marini, C Santi… - Pharmaceutics, 2022 - mdpi.com
This review describes the recently FDA-approved drugs (in the year 2022). Many of these
products contain active moieties that FDA had not previously approved, either as a single …

Kinetically-driven reactivity of sulfinylamines enables direct conversion of carboxylic acids to sulfinamides

HT Dang, A Porey, S Nand, R Trevino… - Chemical …, 2023 - pubs.rsc.org
Sulfinamides are some of the most centrally important four-valent sulfur compounds that
serve as critical entry points to an array of emergent medicinal functional groups, molecular …