Conserved and unique functions of Blimp1 in immune cells
S Nadeau, GA Martins - Frontiers in Immunology, 2022 - frontiersin.org
B-lymphocyte-induced maturation protein-1 (Blimp1), is an evolutionarily conserved
transcriptional regulator originally described as a repressor of gene transcription. Blimp1 …
transcriptional regulator originally described as a repressor of gene transcription. Blimp1 …
CXCR4 hyperactivation cooperates with TCL1 in CLL development and aggressiveness
R Lewis, HC Maurer, N Singh, I Gonzalez-Menendez… - Leukemia, 2021 - nature.com
Aberrant CXCR4 activity has been implicated in lymphoma pathogenesis, disease
progression, and resistance to therapies. Using a mouse model with a gain-of-function …
progression, and resistance to therapies. Using a mouse model with a gain-of-function …
Study on the effect of Ezh2 inhibitor combined with tigit monoclonal antibody against multiple myeloma cells
Z Liu, Y Jia, C Yang, H Liu, H Shen, H Wang… - International Journal of …, 2023 - mdpi.com
EZH2, a member of the polycomb repressive complex 2, induces trimethylation of the
downstream gene at the histone three lysine 27 (H3K27me3) position to inhibit tumor cell …
downstream gene at the histone three lysine 27 (H3K27me3) position to inhibit tumor cell …
Genetic disruption of Blimp-1 drastically augments the antitumor efficacy of BCMA-targeting CAR T cells
Chimeric antigen receptor (CAR) T cells directed against B-cell maturation antigen (BCMA)
are an effective treatment for multiple myeloma (MM), but short persistence and frequent …
are an effective treatment for multiple myeloma (MM), but short persistence and frequent …
Modelling hyperactivated CXCR4 signaling in murine models of indolent and aggressive B cell lymphoma
RI Lewis - 2025 - mediatum.ub.tum.de
Aberrant CXCR4 signaling has been linked to more aggressive presentation in B cell
lymphomas, yet no previous in vivo data existed. Here, we crossbred a murine model of …
lymphomas, yet no previous in vivo data existed. Here, we crossbred a murine model of …
[KSIĄŻKA][B] Estrogen Regulation of Non-Hodgkin Lymphomas and its Underlying Mechanisms
D Huang - 2022 - search.proquest.com
Most non-Hodgkin lymphoma (NHL), including diffuse large B-cell lymphoma (DLBCL) and
mantle cell lymphoma (MCL), show a higher male to female incidence ratio. The reason for …
mantle cell lymphoma (MCL), show a higher male to female incidence ratio. The reason for …