Publisher Summary This chapter focuses on structure and expression of interleukin-6 (IL-6),
which is a cytokine with pleiotropic activities that plays a central role in host defense. IL-6 …

An effective host defense mechanism involves inflammation to eliminate pathogens from the
site of infection, followed by the resolution of inflammation and the restoration of tissue …

Multicentric Castleman's disease (MCD) is an atypical lymphoproliferative disorder defined
using clinical and pathologic criteria. A characteristic of the MCD is a close association with …

Abstract IL-6−/− mice showed impaired leukocyte accumulation in subcutaneous air
pouches. Defective leukocyte accumulation was not due to a reduced migratory capacity of …

Interleukin 6 (iL-6) is a multi-functional cytokine that is produced by a range of cells and
plays a central role in host defense mechanisms. Abnormal production of IL-6 has been …

Abstract Interleukin (IL)-6 is a pleiotropic cytokine that not only affects the immune system,
but also acts in other biological systems and many physiological events in various organs. In …

Interleukin 6 (IL6) plays key roles in hematopoiesis, immune, and acute phase responses.
Dysregulated IL6 expression is implicated in diseases such as atherosclerosis and arthritis …

Many cytokines and cytokine receptors involved in the regulation of hematopoiesis, immune
responses, and inflammation have been identified and characterized at the molecular level …

Abstract Interleukin‐6 (IL‐6) is a multifunctional cytokine that plays a central role in host
defense due to its wide range of immune and hematopoietic activities and its potent ability to …

Cytokines are factors that are known to have both tumor-promoting and inhibitory effects on
breast cancer growth depending presumably on their relative concentrations and the …