The role of epigenetics in psychological resilience

D Smeeth, S Beck, EG Karam, M Pluess - The Lancet Psychiatry, 2021 - thelancet.com
There is substantial variation in people's responses to adversity, with a considerable
proportion of individuals displaying psychological resilience. Epigenetic mechanisms are …

Epigenetic clocks in the pediatric population: when and why they tick?

J Wang, WH Zhou - Chinese Medical Journal, 2021 - mednexus.org
Recent research efforts have provided compelling evidence of genome-wide DNA
methylation alterations in pediatrics. It is currently well established that epigenetic clocks …

Association between the timing of childhood adversity and epigenetic patterns across childhood and adolescence: findings from the Avon Longitudinal Study of …

AA Lussier, Y Zhu, BJ Smith, J Cerutti… - The Lancet Child & …, 2023 - thelancet.com
Background Childhood adversity is a potent determinant of health across development and
is associated with altered DNA methylation signatures, which might be more common in …

[HTML][HTML] Air pollution and epigenetic aging among Black and White women in the US

SH Koenigsberg, CJ Chang, J Ish, Z Xu… - Environment …, 2023 - Elsevier
Background DNA methylation-based measures of biological aging have been associated
with air pollution and may link pollutant exposures to aging-related health outcomes …

Considerations toward an epigenetic and common pathways theory of mental disorder.

JT Nigg - Journal of Psychopathology and Clinical Science, 2023 - psycnet.apa.org
Psychopathology emerges from the dynamic interplay of physiological and mental
processes and ecological context. It can be seen as a failure of recursive, homeostatic …

The effect of polyphenols on DNA methylation-assessed biological age attenuation: the DIRECT PLUS randomized controlled trial

A Yaskolka Meir, M Keller, A Hoffmann, E Rinott… - BMC medicine, 2023 - Springer
Background Epigenetic age is an estimator of biological age based on DNA methylation; its
discrepancy from chronologic age warrants further investigation. We recently reported that …

Epigenetics and ADHD: reflections on current knowledge, research priorities and translational potential

CAM Cecil, JT Nigg - Molecular diagnosis & therapy, 2022 - Springer
Attention-deficit/hyperactivity disorder (ADHD) is a common and debilitating
neurodevelopmental disorder influenced by both genetic and environmental factors …

Early-set POMC methylation variability is accompanied by increased risk for obesity and is addressable by MC4R agonist treatment

L Lechner, R Opitz, MJ Silver, PM Krabusch… - Science translational …, 2023 - science.org
Increasing evidence points toward epigenetic variants as a risk factor for develo** obesity.
We analyzed DNA methylation of the POMC (pro-opiomelanocortin) gene, which is pivotal …

Association of maternal tobacco use during pregnancy with preadolescent brain morphology among offspring

R Zou, OD Boer, JF Felix, RL Muetzel… - JAMA network …, 2022 - jamanetwork.com
Importance Maternal tobacco use during pregnancy has been associated with various
health consequences, including suboptimal neurodevelopment in offspring. However, the …

[HTML][HTML] Green space exposure and blood DNA methylation at birth and in childhood–A multi-cohort study

S Aguilar-Lacasana, IF Marques, M de Castro… - Environment …, 2024 - Elsevier
Green space exposure has been associated with improved mental, physical and general
health. However, the underlying biological mechanisms remain largely unknown. The aim of …