Chemical Biology of H2S Signaling through Persulfidation

MR Filipovic, J Zivanovic, B Alvarez… - Chemical …, 2018 - ACS Publications
Signaling by H2S is proposed to occur via persulfidation, a posttranslational modification of
cysteine residues (RSH) to persulfides (RSSH). Persulfidation provides a framework for …

Physiological implications of hydrogen sulfide: a whiff exploration that blossomed

R Wang - Physiological reviews, 2012 - journals.physiology.org
The important life-supporting role of hydrogen sulfide (H2S) has evolved from bacteria to
plants, invertebrates, vertebrates, and finally to mammals. Over the centuries, however, H2S …

Cysteine-mediated redox signaling: chemistry, biology, and tools for discovery

CE Paulsen, KS Carroll - Chemical reviews, 2013 - ACS Publications
Reactive oxygen, nitrogen, and sulfur species, referred to as ROS, RNS, and RSS,
respectively, are produced during normal cell function and in response to various stimuli. An …

A review of hydrogen sulfide synthesis, metabolism, and measurement: is modulation of hydrogen sulfide a novel therapeutic for cancer?

X Cao, L Ding, Z **e, Y Yang, M Whiteman… - Antioxidants & redox …, 2019 - liebertpub.com
Abstract Significance: Hydrogen sulfide (H2S) has been recognized as the third gaseous
transmitter alongside nitric oxide and carbon monoxide. In the past decade, numerous …

International union of basic and clinical pharmacology. CII: pharmacological modulation of H2S levels: H2S donors and H2S biosynthesis inhibitors

C Szabo, A Papapetropoulos, EH Ohlstein - Pharmacological reviews, 2017 - Elsevier
Over the last decade, hydrogen sulfide (H 2 S) has emerged as an important endogenous
gasotransmitter in mammalian cells and tissues. Similar to the previously characterized …

Redox biochemistry of hydrogen sulfide

O Kabil, R Banerjee - Journal of Biological Chemistry, 2010 - ASBMB
H 2 S, the most recently discovered gasotransmitter, might in fact be the evolutionary
matriarch of this family, being both ancient and highly reduced. Disruption of γ-cystathionase …

[HTML][HTML] Hydrogen sulfide chemical biology: pathophysiological roles and detection

GK Kolluru, X Shen, SC Bir, CG Kevil - Nitric oxide, 2013 - Elsevier
Hydrogen sulfide (H 2 S) is the most recent endogenous gasotransmitter that has been
reported to serve many physiological and pathological functions in different tissues. Studies …

[HTML][HTML] Capture and visualization of hydrogen sulfide via a fluorescent probe

C Liu, J Pan, S Li, Y Zhao, LY Wu… - … (International ed. in …, 2011 - ncbi.nlm.nih.gov
Hydrogen sulfide (H2S) has been known as a toxic pollutant for years. However, this
molecule has been recently recognized as the third gaseous transmitter (the other two are …

Hydrogen sulfide (H 2 S) releasing agents: chemistry and biological applications

Y Zhao, TD Biggs, M **an - Chemical communications, 2014 - pubs.rsc.org
Hydrogen sulfide (H2S) is a newly recognized signaling molecule with very potent
cytoprotective actions. The fields of H2S physiology and pharmacology have been rapidly …

Making and working with hydrogen sulfide: the chemistry and generation of hydrogen sulfide in vitro and its measurement in vivo: a review

MN Hughes, MN Centelles, KP Moore - Free Radical Biology and Medicine, 2009 - Elsevier
Hydrogen sulfide is rapidly emerging as an important vasoactive mediator formed in health
and disease. Its biological action is centered on its reactivity with heme-proteins and its …