Amyotrophic lateral sclerosis

EL Feldman, SA Goutman, S Petri, L Mazzini… - The Lancet, 2022‏ - thelancet.com
Amyotrophic lateral sclerosis is a fatal CNS neurodegenerative disease. Despite intensive
research, current management of amyotrophic lateral sclerosis remains suboptimal from …

Recent advances in the diagnosis and prognosis of amyotrophic lateral sclerosis

SA Goutman, O Hardiman, A Al-Chalabi… - The Lancet …, 2022‏ - thelancet.com
The diagnosis of amyotrophic lateral sclerosis can be challenging due to its heterogeneity in
clinical presentation and overlap with other neurological disorders. Diagnosis early in the …

Whole-brain propagation delays in multiple sclerosis, a combined tractography-magnetoencephalography study

P Sorrentino, S Petkoski, M Sparaco, ET Lopez… - Journal of …, 2022‏ - jneurosci.org
Two structurally connected brain regions are more likely to interact, with the lengths of the
structural bundles, their widths, myelination, and the topology of the structural connectome …

Resting-state EEG reveals four subphenotypes of amyotrophic lateral sclerosis

S Dukic, R McMackin, E Costello, M Metzger, T Buxo… - Brain, 2022‏ - academic.oup.com
Amyotrophic lateral sclerosis is a devastating disease characterized primarily by motor
system degeneration, with clinical evidence of cognitive and behavioural change in up to …

Flexible brain dynamics underpins complex behaviours as observed in Parkinson's disease

P Sorrentino, R Rucco, F Baselice, R De Micco… - Scientific reports, 2021‏ - nature.com
Rapid reconfigurations of brain activity support efficient neuronal communication and
flexible behaviour. Suboptimal brain dynamics is associated to impaired adaptability …

Patterned functional network disruption in amyotrophic lateral sclerosis

S Dukic, R McMackin, T Buxo, A Fasano… - Human Brain …, 2019‏ - Wiley Online Library
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease primarily
affecting motor function, with additional evidence of extensive nonmotor involvement …

Minimum spanning tree analysis of brain networks: A systematic review of network size effects, sensitivity for neuropsychiatric pathology, and disorder specificity

N Blomsma, B de Rooy, F Gerritse… - Network …, 2022‏ - direct.mit.edu
Brain network characteristics' potential to serve as a neurological and psychiatric pathology
biomarker has been hampered by the so-called thresholding problem. The minimum …

Mindfulness meditation is related to long‐lasting changes in hippocampal functional topology during resting state: A magnetoencephalography study

A Lardone, M Liparoti, P Sorrentino, R Rucco… - Neural …, 2018‏ - Wiley Online Library
It has been suggested that the practice of meditation is associated to neuroplasticity
phenomena, reducing age‐related brain degeneration and improving cognitive functions …

Imaging cerebral activity in amyotrophic lateral sclerosis

M Proudfoot, P Bede, MR Turner - Frontiers in neurology, 2019‏ - frontiersin.org
Advances in neuroimaging, complementing histopathological insights, have established a
multi-system involvement of cerebral networks beyond the traditional neuromuscular …