Cerebrovascular pressure autoregulation is the physiologic mechanism that holds cerebral
blood flow (CBF) relatively constant across changes in cerebral perfusion pressure (CPP) …

Cerebral blood flow (CBF) autoregulation is the physiologic process whereby blood supply
to the brain is kept constant over a range of cerebral perfusion pressures ensuring a …

Background Neurodevelopmental disabilities persist in survivors of neonatal hypoxic-
ischemic encephalopathy (HIE) despite treatment with therapeutic hypothermia …

Standard hemodynamic monitoring such as blood pressure and pulse oximetry may only
provide a crude estimation of organ perfusion in the critical care setting. Near-infrared …

Background: Therapeutic hypothermia provides incomplete neuroprotection for neonatal
hypoxic-ischemic encephalopathy (HIE). We examined whether hemodynamic goals that …

Aim Improved survival after cardiac arrest has placed greater emphasis on neurologic
resuscitation. The purpose of this pilot study was to evaluate the relationship between …

To examine the temporal relationship of cortical autophagic flux with delayed neuronal cell
death after hypoxia-ischemia (HI) in neonatal piglets. HI was produced with 45-min hypoxia …

Over a wide range of systemic arterial pressures, cerebral blood flow (CBF) is regulated
fairly constantly by the cerebral vessels in a process termed cerebral autoregulation (CA) …

The brain is important for our survival and identity. It has high metabolic demands and is
therefore particularly vulnerable to hypoxia and hypoglycemia. To prevent injury and …

Acute liver failure (ALF) is a condition that can rapidly progress to multiorgan failure. This
article focuses on the diagnosis and management of ALF. We provide a detailed review of …