Modern anesthetic compounds and advanced monitoring tools have revolutionized the field
of medicine, allowing for complex surgical procedures to occur safely and effectively. Faster …

Infants who undergo surgical procedures in the first few months of life are at a higher risk of
death or subsequent neurodevelopmental abnormalities. Although the pathogenesis of …

Lengthy use of general anesthetics (GAs) causes neurobehavioral deficits in the develo**
brain, which has raised significant clinical concerns such that the United States Food and …

Various lines of evidence suggest that neonatal exposure to general anesthetics, especially
repeatedly, results in neuropathological brain changes and long‐term cognitive impairment …

Dysbiosis of the intestinal microbiota has been shown to result in altered immune responses
and increased susceptibility to infection; as such, the state of the intestinal microbiome may …

The potential long-term effects of anesthesia on cognitive development, especially in
neonates and infants, have raised concerns. However, our understanding of its underlying …

Developmental sevoflurane exposure leads to neuronal cell death, and subsequent learning
and memory cognitive defects. The underlyi\ng mechanism remains to be elucidated …

Background Both animal and retrospective human studies have linked extended and
repeated general anaesthesia during early development with cognitive and behavioural …

Background: Early postnatal exposure to general anesthetics may interfere with brain
development. We tested the hypothesis that isoflurane causes a lasting disruption in myelin …

Epidemiological studies suggest exposures to anesthetic agents and/or sedative drugs
(AASDs) in children under three years old, or pregnant women during the third trimester …