Evidence from preclinical studies suggests that the competitive HMG-CoA reductase
(HMGCR) inhibitors universally known as' statins,'in addition to being powerful drugs that …

Spheroid culture provides cells with a three‐dimensional environment that can better mimic
physiological conditions compared to monolayer culture. Technologies involved in the …

Glioblastoma (GBM) is the deadliest brain tumor for which there is no cure. Bioengineered
GBM models, such as hydrogel-encapsulated spheroids, that capture both cell-cell and cell …

Brain glioma is the most common malignant tumor of the central nervous system, and one of
the leading causes of death in patients with intracranial tumors. The clinical outcome of …

Simple Summary Tumor microenvironment is a major contributor to tumor growth, metastasis
and resistance to therapy. It consists of many cancer-associated fibroblasts (CAFs), which …

Cell therapy is one of the methods that have shown promising results in treating diseases in
recent decades. However, the use of different types of cells comes with limitations. The …

Exosomes (EXOs) are naturally occurring nanosized lipid bilayers that can be efficiently
used as a drug delivery system to carry small pharmaceutical, biological molecules and …

Radiation is utilized in the therapy of more than 50% of cancer patients. Unfortunately, many
malignancies become resistant to radiation over time. We investigated the hypothesis that …

Anticancer drug development is a crucial step toward cancer treatment, that requires realistic
predictions of malignant tissue development and sophisticated drug delivery. Tumors often …

Cell therapy has emerged as one of the most promising approaches to treating disease in
recent decades. The application of stem cells in anti-tumor therapy is determined by their …