This review focuses on the role of oxidative processes in atherosclerosis and its resultant
cardiovascular events. There is now a consensus that atherosclerosis represents a state of …

WITH THE ESSENTIALLY simultaneous cloning in 1989 of the selectins (then called ELAM-
1, GMP-140/PADGEM, and LECAM-l/LAM-1; now called E-selectin, P-selectin, and L …

The transition from neutrophil to mononuclear-cell infiltrate is a hallmark of acute
inflammation. The kinetics of leuko-endothelial adhesion molecule expression and …

Numerous nucleic acid ligands, also termed decoys or aptamers, have been developed
during the past 15 years that can inhibit the activity of many pathogenic proteins. Two of …

The circulatory and migratory properties of white blood cells have evolved to allow efficient
surveillance of tissues for infectious pathogens and rapid accumulation at sites of injury and …

P selectin, expressed on surfaces of activated endothelial cells and platelets, is an adhesion
receptor for leukocytes. We report that P selectin-deficient mice, generated by gene targeting …

L-selectin, a cell adhesion molecule expressed by leukocytes, mediates the attachment of
lymphocytes to high endothelial venules (HEV) of peripheral lymph nodes and mediates the …

Inflammatory mediators in the cervix, placenta and fetal membranes play a crucial role in
human parturition. The aim of this study was to determine whether the upper and lower …

The demonstration of soluble isotorms of adhesion molecules has added a layer of
complexity to our understanding of lymphoid-endothelial cell interactions. This is especially …

The selectin family of adhesion molecules mediates the initial attachment of leukocytes to
venular endothelial cells before their firm adhesion and diapedesis at sites of tissue injury …