For 2 decades fluoroquinolones have been found to be generally well-tolerated and safe.
Adverse events may be inherent to the class or influenced by structural modifications. The …

Levofloxacin (Levaquin®) is a fluoroquinolone antibacterial agent with a broad spectrum of
activity against Gram-positive and Gram-negative bacteria and atypical respiratory …

Background Cellulitis is a condition routinely encountered in the primary care setting. No
previous study has compared a short (5 days) vs standard (10 days) course of therapy of the …

Skin and skin-structure infections are common, and range from minor pyodermas to severe
necrotizing infections. Complicated infections are defined as involving abnormal skin or …

BACKGROUND: Premarketing trials showed the fluoroquinolone agents to have a favorable
side-effect profile, with treatment-related adverse events comprising gastrointestinal, central …

There has been a growing rate of resistance among common urinary tract pathogens, such
as Escherichia coli, to traditional antimicrobial therapies including the “gold standard” …

OBJECTIVE: This paper reviews the literature available on the new fluoroquinolones–
clinafloxacin, gatifloxacin, grepafloxacin, levofloxacin, moxifloxacin, sparfloxacin and …

Staphylococcus aureus is a leading cause of septicemia, endocarditis, pneumonia, skin and
soft tissue infections, bone and joint infections, and hospital-acquired infections. In …

Levofloxacin is the L-form of the fluoroquinolone antibacterial agent, ofloxacin. In in vitro
studies, levofloxacin demonstrated a broad range of activity against Gram-positive and …

Levofloxacin, the optically pure levorotatory isomer of ofloxacin, is a fluoro-quinolone
antibacterial agent. Like other fluoroquinolones, it acts on bacterial topoisomerase and has …