The biogenesis and biological function of PIWI-interacting RNA in cancer

S Chen, S Ben, J **n, S Li, R Zheng, H Wang… - Journal of hematology & …, 2021 - Springer
Small non-coding RNAs (ncRNAs) are vital regulators of biological activities, and aberrant
levels of small ncRNAs are commonly found in precancerous lesions and cancer. PIWI …

[HTML][HTML] Non-coding RNAs in immunoregulation and autoimmunity: Technological advances and critical limitations

D Kumar, SS Sahoo, D Chauss, M Kazemian… - Journal of …, 2023 - Elsevier
Immune cell function is critically dependent on precise control over transcriptional output
from the genome. In this respect, integration of environmental signals that regulate gene …

A review of discovery profiling of PIWI-interacting RNAs and their diverse functions in metazoans

S Huang, K Yoshitake, S Asakawa - International Journal of Molecular …, 2021 - mdpi.com
PIWI-interacting RNAs (piRNAs) are a class of small non-coding RNAs (sncRNAs) that
perform crucial biological functions in metazoans and defend against transposable elements …

[HTML][HTML] piRNAs and PIWI proteins as diagnostic and prognostic markers of genitourinary cancers

K Hanusek, S Poletajew, P Kryst… - Biomolecules, 2022 - mdpi.com
piRNAs (PIWI-interacting RNAs) are small non-coding RNAs capable of regulation of
transposon and gene expression. piRNAs utilise multiple mechanisms to affect gene …

Computational approaches and challenges for identification and annotation of non-coding RNAs using RNA-Seq

K Dindhoria, I Monga, AS Thind - Functional & Integrative Genomics, 2022 - Springer
Significant innovations in next-generation sequencing techniques and bioinformatics tools
have impacted our appreciation and understanding of RNA. Practical RNASeq applications …

[HTML][HTML] Advances in computational methodologies for classification and sub-cellular locality prediction of non-coding RNAs

MN Asim, MA Ibrahim, M Imran Malik, A Dengel… - International Journal of …, 2021 - mdpi.com
Apart from protein-coding Ribonucleic acids (RNAs), there exists a variety of non-coding
RNAs (ncRNAs) which regulate complex cellular and molecular processes. High-throughput …

Computational methods and online resources for identification of piRNA-related molecules

Y Liu, A Li, G **e, G Liu, X Hei - Interdisciplinary sciences: computational …, 2021 - Springer
Abstract piRNAs are a class of small non-coding RNA molecules, which interact with the
PIWI family and have many important and diverse biological functions. The present review is …

[HTML][HTML] Databases and computational methods for the identification of piRNA-related molecules: A survey

C Guo, X Wang, H Ren - Computational and Structural Biotechnology …, 2024 - Elsevier
Piwi-interacting RNAs (piRNAs) are a class of small non-coding RNAs (ncRNAs) that plays
important roles in many biological processes and major cancer diagnosis and treatment …

piRNN: deep learning algorithm for piRNA prediction

K Wang, J Hoeksema, C Liang - PeerJ, 2018 - peerj.com
Piwi-interacting RNAs (piRNAs) are the largest class of small non-coding RNAs discovered
in germ cells. Identifying piRNAs from small RNA data is a challenging task due to the lack of …

PIWI-interacting RNAs in human diseases: databases and computational models

T Zhang, L Chen, R Li, N Liu, X Huang… - Briefings in …, 2022 - academic.oup.com
PIWI-interacting RNAs (piRNAs) are short 21–35 nucleotide molecules that comprise the
largest class of non-coding RNAs and found in a large diversity of species including yeast …