New methods for preparation of tailor-made fluorine-containing compounds are in extremely
high demand in nearly every sector of chemical industry. The asymmetric construction of …

The activation of a substrate by a chiral catalyst is now regarded as one of the most powerful
strategies that can be employed in the art of asymmetric synthesis. 1 The development of …

Phenols are widely used as starting materials in both industrial and academic society.
Dearomatization reactions of phenols provide an efficient way to construct highly …

Taking into account the vast arrays of fluorinated motifs known, 11 this review will be limited
to the monofluorination of organic compounds, ie, synthetic methods allowing the …

1. INTRODUCTION Despite being largely absent from natural products and biological
processes, fluorine plays a conspicuous and increasingly important role within …

Conspectus Dearomatization reactions serve as powerful methods for the synthesis of highly
functionalized, three-dimensional structures starting with simple planar aromatic …

We report herein an operationally simple method for the direct conversion of benzylic C–H
groups to C–F. We show that visible light can activate diarylketones to abstract a benzylic …

This review summarizes the recent advances in the field of asymmetric dearomatization of
phenols and their applications in the total synthesis of some complex natural products. The …

Selective reactions on structures of high complexity can move beyond the mind's eye and
proof-of-principle. Enhanced understanding of noncovalent interactions and their …