Most patients with Alzheimer's disease present with amnestic problems; however, a
substantial proportion, over-represented in young-onset cases, have atypical phenotypes …

Data-driven disease progression models are an emerging set of computational tools that
reconstruct disease timelines for long-term chronic diseases, providing unique insights into …

Background. Alzheimer's disease (AD) is a progressive neurodegenerative disorder
affecting many individuals worldwide with no effective treatment to date. AD is characterized …

Epidemiological studies identify midlife hearing loss as an independent risk factor for
dementia, estimated to account for 9% of cases. We evaluate candidate brain bases for this …

Since the original description of amyloid-β plaques and tau tangles more than 100 years
ago, these lesions have been considered the neuropathological hallmarks of Alzheimer …

Alzheimer's disease (AD) is a progressive, neurodegenerative disorder that affects memory,
thinking, behavior, and other cognitive functions. Although there is no cure, detecting AD …

Purpose of review The study aims to provide a summary of recent developments for
diagnosing and managing posterior cortical atrophy (PCA). We present current efforts to …

Alzheimer's disease can present clinically with either the typical amnestic phenotype or with
atypical phenotypes, such as logopenic progressive aphasia and posterior cortical atrophy …

Introduction This work aims to characterize the sequence in which cognitive deficits appear
in two dementia syndromes. Methods Event‐based modeling estimated fine‐grained …

Alzheimer's disease (AD) is the most common cause of dementia in the elderly, affecting
roughly half of those over the age of 85. We briefly discussed the risk factors, epidemiology …