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Glucose transporters in cancer–from tumor cells to the tumor microenvironment
Solute carriers of the glucose transporter (GLUT) family mediate the first step for cellular
glucose usage. The upregulation of GLUT s has been reported in numerous cancer types as …
glucose usage. The upregulation of GLUT s has been reported in numerous cancer types as …
[HTML][HTML] Lactate in the tumor microenvironment: an essential molecule in cancer progression and treatment
R Pérez-Tomás, I Pérez-Guillén - Cancers, 2020 - mdpi.com
Simple Summary The role of lactate in cancer described by Otto Warburg in 1927 states that
cancer cells uptake high amount of glucose with a marked increase in lactate production …
cancer cells uptake high amount of glucose with a marked increase in lactate production …
Zeb1-induced metabolic reprogramming of glycolysis is essential for macrophage polarization in breast cancer
H Jiang, H Wei, H Wang, Z Wang, J Li, Y Ou… - Cell death & …, 2022 - nature.com
Aerobic glycolysis (the Warburg effect) has been demonstrated to facilitate tumor
progression by producing lactate, which has important roles as a proinflammatory and …
progression by producing lactate, which has important roles as a proinflammatory and …
Exosomal lncRNA TUG1 from cancer-associated fibroblasts promotes liver cancer cell migration, invasion, and glycolysis by regulating the miR-524-5p/SIX1 axis
L Lu, J Huang, J Mo, X Da, Q Li, M Fan, H Lu - Cellular & Molecular Biology …, 2022 - Springer
Background Increasing evidence suggests that taurine upregulated gene 1 (TUG1) is crucial
for tumor progression; however, its role in hepatocellular carcinoma (HCC) and the …
for tumor progression; however, its role in hepatocellular carcinoma (HCC) and the …
YTHDC1-mediated augmentation of miR-30d in repressing pancreatic tumorigenesis via attenuation of RUNX1-induced transcriptional activation of Warburg effect
Y Hou, Q Zhang, W Pang, L Hou, Y Liang… - Cell Death & …, 2021 - nature.com
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal human cancers. It
thrives in a malnourished environment; however, little is known about the mechanisms by …
thrives in a malnourished environment; however, little is known about the mechanisms by …
[HTML][HTML] Targeting the Warburg effect: A revisited perspective from molecular mechanisms to traditional and innovative therapeutic strategies in cancer
M Liao, D Yao, L Wu, C Luo, Z Wang, J Zhang… - … Pharmaceutica Sinica B, 2024 - Elsevier
Cancer reprogramming is an important facilitator of cancer development and survival, with
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
tumor cells exhibiting a preference for aerobic glycolysis beyond oxidative phosphorylation …
PM2. 5 promotes NSCLC carcinogenesis through translationally and transcriptionally activating DLAT-mediated glycolysis reprograming
Q Chen, Y Wang, L Yang, L Sun, Y Wen… - Journal of Experimental …, 2022 - Springer
Background Airborne fine particulate matter (PM2. 5) has been associated with lung cancer
development and progression in never smokers. However, the molecular mechanisms …
development and progression in never smokers. However, the molecular mechanisms …
Hypoxia-induced lncRNA-AC020978 promotes proliferation and glycolytic metabolism of non-small cell lung cancer by regulating PKM2/HIF-1α axis
Q Hua, B Mi, F Xu, J Wen, L Zhao, J Liu… - Theranostics, 2020 - pmc.ncbi.nlm.nih.gov
Rationale: Non-small cell lung cancer (NSCLC) is a deadly disease with a hallmark of
aberrant metabolism. The mechanism of glycolysis associated lncRNA underlying the …
aberrant metabolism. The mechanism of glycolysis associated lncRNA underlying the …
Canonical Wnt signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional complex
F Wang, L Chen, D Kong, X Zhang, S **a, B Liang… - Hepatology, 2024 - journals.lww.com
Canonical Wnt signaling promotes HSC glycolysis and liver fi... : Hepatology Canonical Wnt
signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional …
signaling promotes HSC glycolysis and liver fibrosis through an LDH-A/HIF-1α transcriptional …
Plasmonic alloys reveal a distinct metabolic phenotype of early gastric cancer
Gastric cancer (GC) is a multifactorial process, accompanied by alterations in metabolic
pathways. Non‐invasive metabolic profiling facilitates GC diagnosis at early stage leading to …
pathways. Non‐invasive metabolic profiling facilitates GC diagnosis at early stage leading to …