Schwann cell plasticity regulates neuroblastic tumor cell differentiation via epidermal growth factor-like protein 8

T Weiss, S Taschner-Mandl, L Janker, A Bileck… - Nature …, 2021 - nature.com
Abstract Adult Schwann cells (SCs) possess an inherent plastic potential. This plasticity
allows SCs to acquire repair-specific functions essential for peripheral nerve regeneration …

[HTML][HTML] Silencing of Epidermal Growth Factor-like Domain 8 Promotes Proliferation and Cancer Aggressiveness in Human Ovarian Cancer Cells by Activating ERK …

YJ Song, JE Kim, L Rajbongshi, YS Lim, YJ Ok… - International Journal of …, 2024 - mdpi.com
Ovarian cancer (OC) is the second most common female reproductive cancer and the most
lethal gynecological malignancy worldwide. Most human OCs are characterized by high …

Notch and Hedgehog in the thymus/parathyroid common primordium: Crosstalk in organ formation

M Figueiredo, JC Silva, AS Santos, V Proa… - Developmental …, 2016 - Elsevier
The avian thymus and parathyroids (T/PT) common primordium derives from the endoderm
of the third and fourth pharyngeal pouches (3/4PP). The molecular mechanisms that govern …

Down-regulation of EGFL8 regulates migration, invasion and apoptosis of hepatocellular carcinoma through activating Notch signaling pathway

F Wu, FY Zhang, GQ Tan, WJ Chen, B Huang, L Yan… - BMC cancer, 2021 - Springer
Background Our previous studies have reported the down-regulation of EGFL8 correlates to
the development and prognosis of colorectal and gastric cancer. The present study is carried …

The Agonistic Activity of the Human Epidermal Growth Factor is Reduced by the D46G Substitution

AA Akunevich, VV Khrustalev… - Protein & Peptide …, 2024 - benthamdirect.com
Background Resistance to anti-tumor agents targeting the epidermal growth factor receptor
(EGFR) reduces treatment response and requires the development of novel EGFR …

[HTML][HTML] Integrated miRNA-mRNA analysis provides potential biomarkers for selective breeding in bay scallop (Argopecten irradians)

T Zhao, S Ding, Z Hao, X Wang, Y Zhan, Y Chang - Genomics, 2021 - Elsevier
Growth traits were compared between selected Argopecten irradians (BA) and non-selected
A. irradians (NA; as a control). The results indicated that 1) the BA line exhibited greater …

Molecular characterization and expression analysis of mouse epidermal growth factor-like domain 8

IJ Song, M Ikram, F Subhan… - International …, 2015 - spandidos-publications.com
Epidermal growth factor (EGF)-like (EGFL) domain, a common structural module in
numerous secreted or transmembrane proteins, is generally involved in protein-protein …

Role of Mitf in melanocyte development as determined by a conditional hypomorphic mutation

R Lasseur - 2024 - opinvisindi.is
Establishment of melanocytes, the pigment-producing cells, starts from the multipotent
neural crest cells. Melanoblasts, the melanocyte precursor cells, follow a tight schedule …

Descriptive and functional characterization of epidermal growth factor‑like domain 8 in mouse cortical thymic epithelial cells by integrated analysis of gene expression …

YS Lim, DY Lee, HY Kim, Y Ok… - International …, 2021 - spandidos-publications.com
Epidermal growth factor‑like domain 8 (EGFL8), a newly identified member of the EGFL
family, and plays negative regulatory roles in mouse thymic epithelial cells (TECs) and …

Epidermal Growth Factor-Like Domain-8 (EGFL8) in Mammals: The Story so far

F Subhan, M Naeem, W Sajjad, L Ali, I Tauseef… - Life and …, 2020 - ojs.lifenscience.org
Epidermal growth factor-like domain-8 (EGFL8) also known as vascular endothelial statin-2
(VE-statin-2). It was identified by using retroviral gene entrapment vectors, expressed in …